BCR-ABL T315I mutation
National Institutes of Health
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Abstract 930 Background: Activating mutations in FLT3 are detected in approximately 30 percent of adult acute myeloid leukemia…
The human Philadelphia chromosome (Ph) arises from a translocation between
chromosomes 9 and 22 [t(9;22)(q34;q11)]. The resulting…
Most CML patients are sensitive to Imatinib Mesylate (IM), however, a small fraction develop resistance, mostly through the onset…