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BBR 3171

Known as: ((PtCl(NH3)2)H2N(CH2)6NH2), BBR 3005 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
PEG–lipid–PLGA hybrid nanoparticles loaded with berberine–phospholipid complex to facilitate the oral delivery efficiency
Abstract The natural product berberine (BBR), present in various plants, arouses great interests because of its numerous… 
Highly Cited
2017
Highly Cited
2017
Gut Microbiota-Mediated Personalized Treatment of Hyperlipidemia Using Berberine
Nitroreductases (NRs) are bacterial enzymes that reduce nitro-containing compounds. We have previously reported that NR of… 
2017
2017
Berberine-sonodynamic therapy induces autophagy and lipid unloading in macrophage
Impaired autophagy in macrophages accompanies the progression of atherosclerosis and contributes to lipid loading in plaques and… 
2015
2015
Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice
Berberine (BBR) shows very low plasma levels after oral administration due to its poor absorption by the gastrointestinal tract… 
Review
2014
Review
2014
Antioxidant and Anti-Inflammatory Activities of Berberine in the Treatment of Diabetes Mellitus
Oxidative stress and inflammation are proved to be critical for the pathogenesis of diabetes mellitus. Berberine (BBR) is a… 
Highly Cited
2013
Highly Cited
2013
Characterization, pharmacokinetics, and hypoglycemic effect of berberine loaded solid lipid nanoparticles
The high aqueous solubility, poor permeability, and absorption of berberine (BBR) result in its low plasma level after oral… 
2012
2012
Identification of CYP isozymes involved in benzbromarone metabolism in human liver microsomes
Benzbromarone (BBR) is metabolized to 1′‐hydroxy BBR and 6‐hydroxy BBR in the liver. 6‐Hydroxy BBR is further metabolized to 5,6… 
Highly Cited
2009
Highly Cited
2009
Proteomic analysis reveals a synergistic mechanism of fluconazole and berberine against fluconazole-resistant Candida albicans: endogenous ROS augmentation.
Our previous study showed that concomitant use of berberine (BBR) and fluconazole (FLC) provided a synergistic action against FLC… 
2008
2008
Catheter ablation of bundle branch reentrant ventricular tachycardia.
Highly Cited
2001
Highly Cited
2001
Bundle-Branch Reentry and the Postpacing Interval After Entrainment by Right Ventricular Apex Stimulation: A New Approach to Elucidate the Mechanism of Wide-QRS-Complex Tachycardia With…
Background —Diagnosis of bundle-branch reentry ventricular tachycardia (BBR-VT) by the standard approach is challenging, and this… 
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