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BBI608

Known as: BB608, BBI-608 
 
National Institutes of Health

Papers overview

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2019
2019
PURPOSE Napabucasin (2-acetylfuro-1,4-naphthoquinone or BBI-608) is a small molecule currently being clinically evaluated in… Expand
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2018
2018
Non-small cell lung cancer (NSCLC) is the most common cause of cancer-related deaths worldwide. While partial or complete tumor… Expand
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Review
2017
Review
2017
Napabucasin (BBI608) is an orally administered small molecule that blocks stem cell activity in cancer cells by targeting the… Expand
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Review
2017
Review
2017
Wnt/β-catenin pathway is one of the main/frequent dysregulated pathways in several tumor types, including colon cancer. Aberrant… Expand
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2017
2017
4106Background: Cancer stem cells are fundamentally important for resistance to therapy, recurrence and metastasis. Napabucasin… Expand
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2016
2016
A small population of cells with stem cell-like properties in prostate cancer (PCa), called prostate cancer stem cells (PrCSCs… Expand
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2016
2016
196 Background: Cancer stemness is thought to be associated with resistance to chemotherapies. BBI608, a first-in-class cancer… Expand
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Highly Cited
2015
Highly Cited
2015
Partial or even complete cancer regression can be achieved in some patients with current cancer treatments. However, such initial… Expand
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2015
2015
TPS4139 Background: BBI608 is an orally-administered first-in-class cancer stemness inhibitor. By targeting Stat3, BBI608 blocks… Expand
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2015
2015
4069 Background: BBI608, a first-in-class CSC inhibitor that works through inhibiting Stat3, has shown potent synergistic anti… Expand
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