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BB-10010

Known as: BB 10010, BB10010 
National Institutes of Health

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3 relations

Broader (3)

MonokinesSmall Inducible Cytokine A3cytokine

Papers overview

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2000
2000
Chemical modification of a variant of human MIP-1alpha; implications for dimer structure.
A sequence variant of human MIP-1alpha, in which Asp26 has been replaced by Al alpha, has been chemically modified by the… 
1999
1999
BB-10010, an analogue of macrophage inflammatory protein-1 alpha, reduces proliferation in murine small-intestinal crypts.
BACKGROUND The small-intestinal epithelium, a rapidly proliferating tissue, is highly sensitive to cycle-specific agents such as… 
Highly Cited
1998
Highly Cited
1998
Myeloid progenitor cell proliferation and mobilization effects of BB10010, a genetically engineered variant of human macrophage inflammatory protein-1alpha, in a phase I clinical trial in patients…
Macrophage Inflammatory Protein (MIP)-1alpha is myelosuppressive in vitro and in vivo for hematopoietic stem and immature subsets… 
1998
1998
A Randomized Phase-II Study of BB-10010 (Macrophage Inflammatory Protein- 1) in Patients With Advanced Breast Cancer Receiving 5-Fluorouracil, Adriamycin, and Cyclophosphamide Chemotherapy
BB-10010 is a variant of the human form of macrophage inflammatory protein-1 (MIP-1), which has been shown in mice to block the… 
1998
1998
A randomized phase-II study of BB-10010 (macrophage inflammatory protein- 1alpha) in patients with advanced breast cancer receiving 5-fluorouracil, adriamycin, and cyclophosphamide chemotherapy.
BB-10010 is a variant of the human form of macrophage inflammatory protein-1alpha (MIP-1alpha), which has been shown in mice to… 
1997
1997
A randomized phase II study of BB‐10010: a variant of human macrophage inflammatory protein‐1α for patients receiving high‐dose etoposide and cyclophosphamide for malignant lymphoma and breast cancer
Macrophage inflammatory protein‐1α (MIP‐1α) is a chemokine that can inhibit the cell cycle progression of both primitive… 
1996
1996
BB-10010/MIP-1 alpha in vivo maintains haemopoietic recovery following repeated cycles of sublethal irradiation.
Macrophage inflammatory protein-1 alpha (MIP-1 alpha) is an inhibitor of stem cell proliferation affording protection against… 
1996
1996
The effect of the chemokine rhMIP‐1α, and a non‐aggregating variant BB‐10010, on blast cells from patients with acute myeloid leukaemia
The effects of recombinant macrophage inflammatory protein 1α (rhMIP‐1α) on the proliferation of leukaemic blast cells from… 
Highly Cited
1995
Highly Cited
1995
Mobilization of early hematopoietic progenitor cells with BB-10010: a genetically engineered variant of human macrophage inflammatory protein-1 alpha.
BB-10010 is a genetically engineered variant of human macrophage inflammatory protein-1 alpha with improved solution properties… 
Highly Cited
1995
Highly Cited
1995
BB-10010: an active variant of human macrophage inflammatory protein-1 alpha with improved pharmaceutical properties.
The stem cell inhibitor, macrophage inflammatory protein-1 alpha (MIP-1 alpha) or LD78, protects multipotent hematopoietic… 
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