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B 669

Known as: 2-Phenazinamine, 3-(cyclohexylimino)-3,5-dihydro-N,5-diphenyl-, B-669, B669 
 
National Institutes of Health

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2 relations

Broader (1)

Clofazimine
analogs & derivatives

Papers overview

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1999
1999
Inhibition of potassium transport and growth of mycobacteria exposed to clofazimine and B669 is associated with a calcium-independent increase in microbial phospholipase A2 activity.
Altered phospholipase A2 (PLA2) activity and its relationship to cation (K+, Ca2+) uptake and growth were investigated in… Expand
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1996
1996
The riminophenazines, clofazimine and B669, inhibit potassium transport in gram-positive bacteria by a lysophospholipid-dependent mechanism.
The effects of the riminophenazine antimicrobial agents clofazimine and B669 as well as those of lysophosphatidylcholine (LPC… Expand
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1995
1995
The inhibitory effects of Mycobacterium tuberculosis on MHC class II expression by monocytes activated with riminophenazines and phagocyte stimulants
The expression of MHC class II antigens by peripheral blood monocytes from normal individuals was investigated. Class II… Expand
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1994
1994
The riminophenazine agents clofazimine and B669 reverse acquired multidrug resistance in a human lung cancer cell line.
The potential of the riminophenazine agents clofazimine and B669, at therapeutically relevant concentrations, to reverse P… Expand
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1993
1993
The riminophenazine agents clofazimine and B669 inhibit the proliferation of cancer cell lines in vitro by phospholipase A2-mediated oxidative and nonoxidative mechanisms.
Clofazimine, a riminophenazine antimicrobial agent, and its analogue B669 were investigated for their effects on FaDu cells, a… Expand
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1993
1993
Clofazimine and B669 inhibit the proliferative responses and Na+, K(+)-adenosine triphosphatase activity of human lymphocytes by a lysophospholipid-dependent mechanism.
The relationship between the phospholipase-stimulating and immunosuppressive properties of the riminophenazine anti-mycobacterial… Expand
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1993
1993
An in vitro comparison of the effects of the prooxidative riminophenazines clofazimine and B669 on neutrophil phospholipase A2 activity and superoxide generation.
The effects of the antimycobacterial agent clofazimine and its experimental analogue B669 on the phospholipase A2 activity of and… Expand
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Highly Cited
1992
Highly Cited
1992
Antimicrobial activities of clofazimine and B669 are mediated by lysophospholipids.
The susceptibilities of a range of gram-positive and gram-negative microbial pathogens to clofazimine and its analog B669 (0.1 to… Expand
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1989
1989
Investigation of the structural properties of dihydrophenazines which contribute to their pro-oxidative interactions with human phagocytes.
Twenty-six dihydrophenazine compounds, including clofazimine, were investigated, at a fixed concentration of 1 mg/l, for their… Expand
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Review
1986
Review
1986
Bacterial periplasmic transport systems: structure, mechanism, and evolution.
  • G. F. Ames
  • Annual review of biochemistry
  • 1986
    • Corpus ID: 8499820
RAHAL J1. Effect of combined therapy with ansamycin, clofazimine, ethambutol, and isoniazid for Mycobacterium avium infection in… Expand
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