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Aztreonam Lysine

A formulation of the synthetic monobactam antibiotic, aztreonam and lysine used in an inhaled form for the treatment of chronic airway infections by… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Inhaled aztreonam lysine versus inhaled tobramycin in cystic fibrosis. An economic evaluation.
RATIONALE Pseudomonas aeruginosa infection is a significant cause of morbidity and mortality in patients with cystic fibrosis and… 
Review
2015
Review
2015
Evidence for the efficacy of aztreonam for inhalation solution in the management of Pseudomonas aeruginosa in patients with cystic fibrosis
Chronic airway infection in cystic fibrosis (CF) is a main cause of the increased morbidity and mortality found with this disease… 
Review
2014
Review
2014
The evidence base for non‐CF bronchiectasis is finally evolving
A meaningful meta-analysis demonstrating consistent positive outcomes for a single therapeutic approach in non-cystic fibrosis… 
2013
2013
Two phase 3 placebo-controlled trials of aztreonam lysine for inhalation (AZLI) for non-cystic fibrosis bronchiectasis (NCFB)
INTRODUCTION: We report the results of AIR-BX 1 and AIR-BX2, two randomized, double-blind, placebo-controlled international… 
Review
2012
Review
2012
Aztreonam lysine for inhalation: new formulation of an old antibiotic.
PURPOSE The pharmacology, safety, efficacy, pharmacokinetics, pharmacodynamics, current place in therapy, and potential future… 
Review
2012
Review
2012
Inhaled Aztreonam Lysine for Cystic Fibrosis Pulmonary Disease–Related Outcomes
OBJECTIVE: To evaluate the pharmacology, clinical efficacy, and safety of aztreonam lysine for inhalation (AZLI) for cystic… 
2012
2012
Aerosolized antibiotics: the past, present and future, with a special emphasis on inhaled colistin
Inhaled antibiotics, such as TOBI (a tobramycin solution), gentamicin, colistin and aztreonam lysine (Cayston) have been… 
Review
2012
Review
2012
Inhaled Aztreonam Lysine for Cystic Fibrosis
Objective: To review the mechanism of action, indication, pharmacokinetics, clinical efficacy, safety and tolerability, dosing… 
2011
2011
Aztreonam Lysine for Inhalation Solution in Cystic Fibrosis
Aztreonam is a monobactam antibacterial with bactericidal activity against a wide range of aerobic Gram-negative bacteria… 
Review
2010
Review
2010
Aztreonam Lysine for Inhalation Solution
Aztreonam is a monobactam antibacterial with bactericidal activity against a wide range of aerobic Gram-negative bacteria… 
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