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Azacosterol

Known as: Androst-5-en-3-ol, 17-((3-(dimethylamino)propyl)methylamino)-, (3beta,17beta)-, IMD 760, 20,25 Diazacholesterol 
A sterol derivative of cholesterol with two nitrogen atoms replacing two carbon atoms that acts as a hypocholesteremic agent by blocking delta-24… 
National Institutes of Health

Related topics

Related topics

10 relations

Broader (1)

Anticholesteremic Agents
Azacosterol HydrochlorideIn Bloodagonistsanalogs & derivatives

Narrower (1)

Diazacholesterol Dihydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Low voltage IMD-TDDB lifetime model for advanced future logic technology nodes
Scaled advanced technologies with its narrow metal line spaces are prone to very wide variation. Therefore, having an accurate… 
2008
2008
Improving the quality of INSAT derived quantitative precipitation estimates using an neural network method
In this paper an Artificial Neural Network (NN) approach has been applied to improve the quality of the INSAT derived sub… 
1985
1985
3-Alkyl-3-hydroxyglutaric acids: a new class of hypocholesterolemic HMG CoA reductase inhibitors. 1.
Derivatives of 3-hydroxy-3-methylglutaric acid (HMG), a portion of the substrate for HMG CoA reductase, were prepared and tested… 
Review
1979
Review
1979
Dagen des oordeels. Pathokinetic mechanisms and molecular messengers (a dramatic view).
To stimulate creative thinking about, and further modeling of, pathokinetic mechanisms, two devices are used herein… 
1977
1977
Induction of HMG CoA reductase by the administration of 20,25-diazacholesterol.
This paper describes the direct examination of HMG CoA reductase activity in rats treated with 20,25-diazacholesterol. Conversion… 
1976
1976
Desmosterol in human and experimental brain tumors in tissue culture.
Desmosterol, a possible chemical indicator of brain tumors, was detected in cells of neurogenic, nitrosourea-induced rat tumors… 
1971
1971
Hypocholesterolemic agents. 7. The C-17 epimer of 20,25-diazacholesterol.
1970
1970
The properties of sarcoplasmic vesicles from rats with 20,25-diazacholesterol induced myotonia.
The calcium transport system of sarcoplasmic vesicles isolated from rats which have been treated with 20,25-diazacholesterol to… 
1965
1965
20, 25-DIAZACHOLESTENOL DIHYDROCHLORIDE. INHIBITION OF CHOLESTEROL BIOSYNTHESIS IN HYPERLIPEMIC SUBJECTS.
THE QUEST for the ideal inhibitor of cholesterol biosynthesis continues. To date, the clinical use of such inhibitors has… 
1965
1965
THE HYPOCHOLESTEROLEMIC ACTION OF 20,25-DIAZACHOLESTEROL.