Axin Signaling Complex

Known as: BDC, Axin-APC-beta-catenin-GSK3B complex, beta-Catenin Destruction Complex 
A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
The association of p120 catenin (p120) with the juxtamembrane domain (JMD) of the cadherin cytoplasmic tail is critical for the… (More)
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Highly Cited
2008
Highly Cited
2008
Pulmonary fibrosis, in particular idiopathic pulmonary fibrosis (IPF), results from aberrant wound healing and scarification. One… (More)
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Highly Cited
2007
Highly Cited
2007
Aberrant WNT signal transduction is involved in many diseases. In colorectal cancer and melanoma, mutational disruption of… (More)
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Highly Cited
2003
Highly Cited
2003
Metal-organic framework-5 (MOF-5) of composition Zn4O(BDC)3 (BDC = 1,4-benzenedicarboxylate) with a cubic three-dimensional… (More)
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Highly Cited
2002
Highly Cited
2002
The Wnt/beta-catenin signaling pathway plays multiple roles during embryonic development, only a few of which have been… (More)
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Highly Cited
2002
Highly Cited
2002
Wnt signals control decisive steps in development and can induce the formation of tumors. Canonical Wnt signals control the… (More)
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Highly Cited
2001
Highly Cited
2001
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that have been implicated in a variety of… (More)
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Highly Cited
2000
Highly Cited
2000
RhoA organizes actin stress fibres and is necessary for cell transformation by oncogenes such as src and ras. Moreover, RhoA is… (More)
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Highly Cited
1995
Highly Cited
1995
In this paper we report that the assembly of interendothelial junctions containing the cell type-specific vascular endothelial… (More)
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Highly Cited
1991
Highly Cited
1991
In this paper, we introduce and analyze robustness measures for the stability of discrete-time systems x(t+1) = Ax(t) under… (More)
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