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Autoimmune Primary Adrenal Insufficiency

Known as: Addison's Disease, Autoimmune Addison's Disease, Autoimmune Adrenalitis 
Diminished production of adrenocortical hormones due to autoimmune destruction of the adrenal glands.
National Institutes of Health

Related topics

Related topics

9 relations
Abdominal CavityAddison DiseaseAdrenal GlandsAdrenal gland hypofunction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Primary adrenal insufficiency is associated with impaired natural killer cell function: a potential link to increased mortality
Objective Mortality in patients with primary adrenal insufficiency (PAI) is significantly increased, with respiratory infections… 
Highly Cited
2013
Highly Cited
2013
Ipilimumab-induced autoimmune adrenalitis.
2009
2009
T cell responses to steroid cytochrome P450 21-hydroxylase in patients with autoimmune primary adrenal insufficiency.
CONTEXT Autoimmune Addison's disease is thought to result from T cell mediated autoimmunity. Autoantibodies against the… 
Highly Cited
2008
Highly Cited
2008
Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency.
CONTEXT/OBJECTIVES It is known that different autoimmune diseases often share the same susceptibility genes. In this study we… 
Review
2005
Review
2005
Management of adrenal insufficiency in different clinical settings
Adrenal insufficiency is a rare disease, but its prevalence is increasing. The most frequent cause of primary adrenal… 
Highly Cited
2005
Highly Cited
2005
Elevated serum interferon-gamma-inducible chemokine-10/CXC chemokine ligand-10 in autoimmune primary adrenal insufficiency and in vitro expression in human adrenal cells primary cultures after…
Chemokines are a large family of cytokines involved in the pathogenesis of inflammatory and autoimmune diseases. Among CXC… 
Highly Cited
2003
Highly Cited
2003
Autoantibodies to steroidogenic enzymes in patients with premature ovarian failure with and without Addison's disease.
DESIGN Adrenal cortex autoantibodies (ACA), steroid-producing cell autoantibodies (StCA) and autoantibodies (Abs) to… 
Highly Cited
1995
Highly Cited
1995
Associated autoimmunity in Addison's disease.
As the last extensive series of patients with Addison's disease and coincident autoimmune phenomena were published approximately… 
Highly Cited
1992
Highly Cited
1992
T and B cell reactivity to adrenal antigens in autoimmune Addison's disease
Autoimmune Addison's disease is a rare condition of uncertain pathogcncsis. To delineate potential autoantigens. an adrenal… 
Highly Cited
1975
Highly Cited
1975
The cytotoxic effect of serum from patients with Addison's disease and autoimmune ovarian failure on human granulosa cells in culture.
Human granulosa cells growing in culture were used to study the effects of sera from twenty-three patients with idiopathic… 
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