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Aquaporin 2

Known as: Aquaporin CD, Aquaporin-2, Aquaporin-CD 
Aquaporin 2 is a water-specific channel protein that is expressed in KIDNEY COLLECTING DUCTS. The translocation of aquaporin 2 to the apical PLASMA… 
National Institutes of Health

Related topics

Related topics

12 relations
AQP2 geneIn BloodNephrogenic Diabetes InsipidusProcess of secretion

Narrower (1)

AQP2 protein, human

Broader (1)

Ion Channel

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Molecular mechanisms regulating aquaporin-2 in kidney collecting duct.
The kidney collecting duct is an important renal tubular segment for regulation of body water homeostasis and urine concentration… 
Highly Cited
2006
Highly Cited
2006
Short-chain ubiquitination mediates the regulated endocytosis of the aquaporin-2 water channel
To regulate mammalian water homeostasis, arginine-vasopressin (AVP) induces phosphorylation and thereby redistribution of renal… 
Review
2006
Review
2006
Regulation of arginine vasopressin in the syndrome of inappropriate antidiuresis.
Review
2003
Review
2003
The ins and outs of aquaporin-2 trafficking.
This review outlines recent advances related to the molecular mechanisms and pathways of aquaporin-2 (AQP2) water channel… 
Highly Cited
2002
Highly Cited
2002
The Role of Putative Phosphorylation Sites in the Targeting and Shuttling of the Aquaporin-2 Water Channel*
In renal collecting ducts, a vasopressin-induced cAMP increase results in the phosphorylation of aquaporin-2 (AQP2) water… 
Highly Cited
1997
Highly Cited
1997
Upregulation of aquaporin-2 water channel expression in chronic heart failure rat.
Aquaporin-2 (AQP2) mediates vasopressin-regulated collecting duct water permeability. Chronic heart failure (CHF) is… 
Highly Cited
1997
Highly Cited
1997
Protein kinase A phosphorylation is involved in regulated exocytosis of aquaporin-2 in transfected LLC-PK1 cells.
Vasopressin-dependent translocation of aquaporin-2 (AQP2) between intracellular vesicles and the plasma membrane has been… 
Review
1996
Review
1996
Pathophysiology of the aquaporin water channels.
Discovery of aquaporin water channel proteins has provided insight into the molecular mechanism of membrane water permeability… 
Highly Cited
1995
Highly Cited
1995
Urinary excretion of aquaporin-2 in patients with diabetes insipidus.
BACKGROUND Urine-concentrating ability is regulated by vasopressin. Recently, the specific water-channel protein of the renal… 
Highly Cited
1995
Highly Cited
1995
Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla.
Lithium, a widely used treatment for bipolar affective disorders, often causes nephrogenic diabetes insipidus. The effect of… 
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