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Apligraf

National Institutes of Health

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Apligraf application (procedure)

Broader (1)

Collagen

Papers overview

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2011
2011
Epidermal stem cells are preserved during commercial-scale manufacture of a bilayered, living cellular construct (Apligraf®).
It is unknown if epidermal stem cells are maintained during the commercial-scale manufacture of Apligraf, a bilayered living… 
2010
2010
Initial clinical experience using a novel ultraportable negative pressure wound therapy device.
UNLABELLED  Background. Traditional negative pressure wound therapy (NPWT) devices, such as the electrically powered V.A.C… 
Review
2002
Review
2002
Bilayered bioengineered skin substitute (Apligraf): a review of its use in the treatment of venous leg ulcers and diabetic foot ulcers.
UNLABELLED The bilayered bioengineered skin substitute (BBSS) [Apligraf] is used for the treatment of venous leg ulcers and… 
2002
2002
The role of graftskin (Apligraf) in difficult-to-heal venous leg ulcers.
A relatively recent option for treating leg ulcers that have lasted longer than a month is to use living bilayered skin… 
2002
2002
Modulating Diseased Skin with Tissue Engineering: Actinic Purpura Treated with Apligraf
BACKGROUND Actinic purpura (AP) is an important medical issue and quality of life issue in the elderly. Current treatment of AP… 
2001
2001
Cost-effectiveness of Apligraf in the treatment of venous leg ulcers.
Venous ulcers are the most common chronic wounds of the lower leg. Skin substitutes recently have been introduced to stimulate… 
2000
2000
Use of human skin equivalent Apligraf for in vitro assessment of cumulative skin irritation potential of topical products.
The main goal of the present study was to investigate the response of the human skin equivalent Apligraf in vitro to the… 
2000
2000
Health-related quality of life in venous leg ulcer patients successfully treated with Apligraf: a pilot study.
Apligraf (Graftskin) is a bilayered, living human skin construct that is indicated for use with standard therapeutic compression… 
Highly Cited
1998
Highly Cited
1998
Tissue engineered skin : Apligraf, a bi-layered living skin equivalent
Driven by the need for a readily available, non-immunological tissue that possesses many of the characteristics of normal human… 
Review
1998
Review
1998
Tissue engineering and the development of Apligraf a human skin equivalent.
In recent years, skin grafting has evolved from the initial autograft and allograft preparations to biosynthetic and tissue… 
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