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Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome
Known as:
Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome [Chemical/Ingredient]
, Anapc1
, Apc1 Subunit, Anaphase-Promoting Complex
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The largest subunit of the anaphase-promoting complex. It acts primarily as a scaffold for the proper organization and arrangement of subunits. The C…
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National Institutes of Health
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Related topics
Related topics
9 relations
ANAPC1 gene
In Blood
Process of secretion
agonists
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Genetic Variants Associated With Corneal Biomechanical Properties and Potentially Conferring Susceptibility to Keratoconus in a Genome-Wide Association Study.
A. Khawaja
,
Karla E. Rojas López
,
+12 authors
P. Hysi
JAMA ophthalmology
2019
Corpus ID: 195696214
Importance Keratoconus is an important cause of visual loss in young adults, but little is known about its genetic causes…
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2019
2019
Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density
Erna V. Ivarsdottir
,
S. Benonisdottir
,
+13 authors
K. Stefánsson
Nature Communications
2019
Corpus ID: 84186177
The corneal endothelium is vital for transparency and proper hydration of the cornea. Here, we conduct a genome-wide association…
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Highly Cited
2016
Highly Cited
2016
Upregulated expression of BCL2, MCM7, and CCNE1 indicate cisplatin-resistance in the set of two human bladder cancer cell lines: T24 cisplatin sensitive and T24R2 cisplatin resistant bladder cancer…
Sung Han Kim
,
Jin-Nyoung Ho
,
+6 authors
S. Byun
Investigative and Clinical Urology
2016
Corpus ID: 14791013
Purpose The mechanism of resistance to cisplatin during treatment of bladder cancer (BC) has been a subject of intense…
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2015
2015
The Role of the Anaphase-Promoting Complex/Cyclosome in Plant Growth
Nubia B. Eloy
,
Marcelo de Freitas Lima
,
P. Ferreira
,
D. Inzé
2015
Corpus ID: 53985704
The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit E3 ubiquitin ligase that plays a major role in the…
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Highly Cited
2014
Highly Cited
2014
Co‐regulation proteomics reveals substrates and mechanisms of APC/C‐dependent degradation
Sasha A. Singh
,
Dominic Winter
,
+6 authors
H. Steen
EMBO Journal
2014
Corpus ID: 10789688
Using multiplexed quantitative proteomics, we analyzed cell cycle‐dependent changes of the human proteome. We identified >4,400…
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2014
2014
Cognition and Hippocampal Plasticity in the Mouse Is Altered by Monosomy of a Genomic Region Implicated in Down Syndrome
I. Sahún
,
D. Marechal
,
+6 authors
Y. Hérault
Genetics
2014
Corpus ID: 13265494
Down syndrome (DS) is due to increased copy number of human chromosome 21. The contribution of different genetic regions has been…
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2013
2013
Coexpression and coregulation analysis of time-series gene expression data in estrogen-induced breast cancer cell
Anirban Bhar
,
Martin Haubrock
,
A. Mukhopadhyay
,
U. Maulik
,
S. Bandyopadhyay
,
E. Wingender
Algorithms for Molecular Biology
2013
Corpus ID: 17315722
BackgroundEstrogen is a chemical messenger that has an influence on many breast cancers as it helps cells to grow and divide…
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2013
2013
The Arabidopsis anaphase-promoting complex/cyclosome subunit 1 is critical for both female gametogenesis and embryogenesis(F).
Yanbing Wang
,
Yingnan Hou
,
+4 authors
Li-jia Qu
Journal of Integrative Plant Biology
2013
Corpus ID: 10321227
Anaphase-promoting complex/cyclosome (APC/C), a multisubunit E3 ligase, plays a critical role in cell cycle control, but the…
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2008
2008
Methylation status of ANAPC1, CDKN2A and TP53 promoter genes in individuals with gastric cancer.
E. M. Lima
,
M. Leal
,
+6 authors
C. Casartelli
Brazilian journal of medical and biological…
2008
Corpus ID: 10747622
Gastric cancer is the forth most frequent malignancy and the second most common cause of cancer death worldwide. DNA methylation…
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Review
2006
Review
2006
Spindle checkpoint function and cellular sensitivity to antimitotic drugs
Hiroshi Y. Yamada
,
G. Gorbsky
Molecular Cancer Therapeutics
2006
Corpus ID: 6398088
Microtubule inhibitors such as Vinka alkaloids (e.g., vinblastine and vincristine) and Taxans (e.g., taxol/paclitaxel and…
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