FAQ

Antibody-drug Conjugate ADCT-402

Known as: ADC ADCT-402, ADCT-402, Anti-CD19 PBD-conjugate ADCT-402 
An antibody-drug conjugate (ADC) consisting of an anti-CD19 humanized monoclonal antibody conjugated, via a cleavable linker comprised of valine… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1995-2018
01219952018

Papers overview

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2018
2018
ADCT-402, a PBD dimer-containing antibody drug conjugate targeting CD19-expressing malignancies.
Human CD19 antigen is a 95-kDa type I membrane glycoprotein in the immunoglobulin superfamily whose expression is limited to the… (More)
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2018
2018
A novel prenyl-polybasic domain code determines lipid-binding specificity of the K-Ras membrane anchor.
Ras proteins must localize to the plasma membrane (PM) for biological function. The membrane anchor of the K-Ras4B isoform… (More)
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2016
2016
A novel bisindole-PBD conjugate inhibits angiogenesis by regulating STAT3 and VEGF in breast cancer cells.
AIMS Breast cancer is highly resistant to chemotherapeutic approach and hence, alternative strategies have been developed to… (More)
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2001
2001
Separation of selected basic pharmaceuticals by reversed-phase and ion-exchange chromatography using thermally tuned tandem columns.
The separation of basic pharmaceuticals is usually performed on C8 or C18 bonded silica supports. Silanolphilic interactions… (More)
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1995
1995
Mixed-mode retention of peptides on phosphate-modified polybutadiene-coated zirconia.
Zirconia HPLC packing materials were found to be potentially advantageous for large-scale protein separations due to their… (More)
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