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Antibody-drug Conjugate ABBV-085
Known as:
ABBV-085
, ADC ABBV-085
An antibody-drug conjugate (ADC) composed of a proprietary monoclonal antibody against a tumor-associated antigen (TAA) linked to an as of yet…
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National Institutes of Health
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2019
2019
First-in-human phase 1 study of ABBV-085, an antibody-drug conjugate (ADC) targeting LRRC15, in sarcomas and other advanced solid tumors.
G. Demetri
,
J. Luke
,
+12 authors
A. Tolcher
Journal of Clinical Oncology
2019
Corpus ID: 190863639
3004 Background: ABBV-085 is an ADC (conjugated to monomethyl auristatin E, drug:antibody ratio of 2:1) directed against leucine…
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2016
2016
ABBV-085 is a novel antibody–drug conjugate (ADC) that targets LRRC15 in the tumor microenvironment
J. Purcell
,
J. Hickson
,
+17 authors
K. Gish
2016
Corpus ID: 78399516
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