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Anti-nectin-4 Monoclonal Antibody-Drug Conjugate AGS-22M6E

Known as: AGS-22M6E 
An antibody drug conjugate (ADC) containing a fully human monoclonal antibody AGS-22 targeting the cell adhesion molecule nectin-4 and conjugated… 
National Institutes of Health

Papers overview

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2012
2012
Purification, crystallization and preliminary X-ray analysis of the IgV domain of human nectin-4.
Nectin-4 belongs to a family of immunoglobulin-like cell adhesion molecules and is highly expressed in cancer cells. Recently… 
2011
2011
Abstract 2832: Development of AGS-22M6E, a novel antibody drug conjugate (ADC) targeting Nectin-4 for the treatment of solid tumors
Nectin-4 is a type I transmembrane antigen identified by Agensys to be highly expressed at the RNA level in a significant number… 
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