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Anti-LGR5 Monoclonal Antibody BNC101
Known as:
BNC-101
, BNC101
, ET-101
A humanized monoclonal antibody targeting leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5), with potential antineoplastic activity…
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National Institutes of Health
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Related topics
Related topics
1 relation
antigen binding
Papers overview
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2017
2017
Bionomics Presents Promising BNC 101 Data at American Association for Cancer Research Conference
R. Michelson
,
B. D. Giacco
2017
Corpus ID: 170076563
LGR5 is a well characterised marker of intestinal stem cells found at the base of intestinal crypts and a receptor for Rspondins…
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2015
2015
Abstract 2315: The LGR5 monoclonal antibody BNC101 has anti-tumor and anti-cancer stem cell activity in pancreatic cancer
F. Shojaei
,
C. Walsh
,
+7 authors
P. Chu
2015
Corpus ID: 56885372
BNC101 is a humanized monoclonal antibody (mAb) targeting LGR5 that has successfully completed IND-enabling studies for upcoming…
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2015
2015
Abstract 2639: Preclinical evaluation and biomarker identification for the anti-LGR5 mAb BNC101 in K-Ras mutant CRC and other solid tumor indications
P. Chu
,
Kristen M Smith
,
+4 authors
Christopher Reyes
2015
Corpus ID: 79061704
2014
2014
Abstract 3894: Targeting colorectal and pancreatic cancer stem cells with the LGR5 monoclonal antibody BNC101
P. Chu
,
Kristen M Smith
,
+4 authors
Christopher Reyes
2014
Corpus ID: 73081294
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA BNC101 is a monoclonal antibody (mAb) targeting LGR5…
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