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Anti-IL-1 alpha Monoclonal Antibody MABp1

Known as: Anti-IL-1 Alpha Monoclonal Antibody, Anti-IL1a Monoclonal Antibody, MABp1 
A human IgG1 monoclonal antibody directed against interleukin-1 alpha (IL1a) with potential A human IgG1 monoclonal antibody targeting the… Expand
National Institutes of Health

Related topics

Related topics

1 relation
antigen binding

Papers overview

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2017
2017
MABp1 as a novel antibody treatment for advanced colorectal cancer: a randomised, double-blind, placebo-controlled, phase 3 study.
BACKGROUND MABp1, an antibody that targets interleukin 1α, has been associated with antitumour activity and relief of… Expand
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2017
2017
MABp1 Targeting IL-1α for Moderate to Severe Hidradenitis Suppurativa Not Eligible for Adalimumab: A Randomized Study.
Patients with moderate to severe hidradenitis suppurativa failing adalimumab therapy, or those ineligible to receive it, remain a… Expand
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Highly Cited
2014
Highly Cited
2014
MABp1, a first-in-class true human antibody targeting interleukin-1α in refractory cancers: an open-label, phase 1 dose-escalation and expansion study.
BACKGROUND Inflammation is an important feature of the malignant phenotype and promotes angiogenesis, tumour invasiveness… Expand
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2012
2012
The mammalian actin-binding protein 1 is critical for spreading and intraluminal crawling of neutrophils under flow conditions.
Recently, the mammalian actin-binding protein 1 (mAbp1; Hip-55, SH3P7, debrin-like protein) was identified as a novel component… Expand
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2010
2010
Trigeminocardiac reflex during Le Fort I osteotomy: a case-crossover study.
OBJECTIVE The present study aimed to assess the occurrence of trigeminocardiac reflex (TCR) during Le Fort I osteotomies. STUDY… Expand
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2006
2006
SH3P7/mAbp1 deficiency leads to tissue and behavioral abnormalities and impaired vesicle transport.
The intracellular adaptor protein SH3P7 is the mammalian ortholog of yeast actin-binding protein 1 and thus alternatively named… Expand
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2003
2003
Mammalian actin binding protein 1 is essential for endocytosis but not lamellipodia formation: functional analysis by RNA interference.
Mammalian actin binding protein 1 (mAbp1, also called SH3P7/Hip55) is structurally and functionally related to yeast Abp1 and to… Expand
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Highly Cited
2002
Highly Cited
2002
Golgi vesicle proteins are linked to the assembly of an actin complex defined by mAbp1.
Recent studies indicate that regulation of the actin cytoskeleton is important for protein trafficking, but its precise role is… Expand
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Highly Cited
2001
Highly Cited
2001
Mammalian Abp1, a Signal-Responsive F-Actin–Binding Protein, Links the Actin Cytoskeleton to Endocytosis via the Gtpase Dynamin
The actin cytoskeleton has been implicated in endocytosis, yet few molecular links to the endocytic machinery have been… Expand
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Highly Cited
2000
Highly Cited
2000
Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation.
Yeast Abp1p is a cortical actin cytoskeleton protein implicated in cytoskeletal regulation, endocytosis, and cAMP-signaling. We… Expand
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