Anti-EphA2 Monoclonal Antibody-MMAF Immunoconjugate MEDI-547

Known as: 1C1-mcMMAF 
An auristatin analogue immunoconjugate directed against Eph receptor A2 (EphA2)-positive cancer cells with potential antineoplastic activity. Anti… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2006-2017
0120062017

Papers overview

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2017
2017
The targeting of therapeutics specifically to diseased tissue is crucial for the development of successful cancer treatments. The… (More)
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2009
2009
BACKGROUND EphA2 is overexpressed in many types of human cancer but is absent or expressed at low levels in normal epithelial… (More)
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2008
2008
The EphA2 receptor tyrosine kinase is selectively expressed on the surface of many different human tumors. We have previously… (More)
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Highly Cited
2006
Highly Cited
2006
The chimeric anti-CD30 monoclonal antibody cAC10, linked to the antimitotic agents monomethyl auristatin E (MMAE) or F (MMAF… (More)
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