Anti-EphA2 Monoclonal Antibody-MMAF Immunoconjugate MEDI-547

Known as: 1C1-mcMMAF

An auristatin analogue immunoconjugate directed against Eph receptor A2 (EphA2)-positive cancer cells with potential antineoplastic activity. Anti…

National Institutes of Health

Papers overview

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2007

CD22 is a B-cell specific antigen expressed on both normal and malignant cells. It is internalized rapidly upon binding to its…

2006

1991 Antibody-drug conjugates (ADC) with linker systems that are highly stable in circulation provide an effective and efficient…