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Anti-EphA2 Monoclonal Antibody-MMAF Immunoconjugate MEDI-547
Known as:
1C1-mcMMAF
An auristatin analogue immunoconjugate directed against Eph receptor A2 (EphA2)-positive cancer cells with potential antineoplastic activity. Anti…
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National Institutes of Health
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MEDI-547
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2007
2007
Non-Clinical Pharmacology of Anti-CD22 Antibody Drug Conjugates.
D. Xie
,
Jakub Baudys
,
+16 authors
S. Prabhu
2007
Corpus ID: 78544741
CD22 is a B-cell specific antigen expressed on both normal and malignant cells. It is internalized rapidly upon binding to its…
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2006
2006
Enhanced in vivo drug-linker stability of an anti-CD70 auristatin immunoconjugate
R. Sanderson
,
S. Alley
,
+5 authors
P. Senter
2006
Corpus ID: 201970995
1991 Antibody-drug conjugates (ADC) with linker systems that are highly stable in circulation provide an effective and efficient…
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