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Anti-CEA/CD3 Bispecific Antibody RO6958688

Known as: RO6958688 
An anti-carcinoembryonic antigen (CEA)/anti-CD3 bispecific monoclonal antibody with potential antineoplastic activity. Anti-CEA/CD3 monoclonal… 
National Institutes of Health

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Related topics

1 relation
antigen binding

Papers overview

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2017
2017
Pharmacokinetics (PK) and pharmacodynamics (PD) of a novel carcinoembryonic antigen (CEA) T-cell bispecific antibody (CEA CD3 TCB) for the treatment of CEA-expressing solid tumors.
2549Background: CEA CD3 TCB (RO6958688) targets CEA on tumor cells and is agonistic for CD3e on T cells. In mouse models, CEA CD3… 
2016
2016
Abstract 1494: Combination of CEA TCB, a novel T-cell bispecific antibody for the treatment of solid tumors, with PD-L1 checkpoint blockade
Recent results from clinical trials have shown that immune therapies, particularly immune checkpoint inhibitors, can extend the… 
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