Aluminum Hydroxide

Known as: Al(OH)3, aluminum hydroxide antacid, Hydrated Alumina 
An inorganic compound containing aluminum. Used in various immunologic preparations to improve immunogenicity, aluminum hydroxide adjuvant consists… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1939-2018
010020019392017

Related topics

Related topics

46 relations

Narrower (31)

AlgiconAlhydrogelAlminoxAludrox
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Aluminum Hydroxide / magnesium trisilicateAluminum Hydroxide 160 MG / magnesium carbonate 105 MG Chewable Tablet [Acid Gone]Aluminum Hydroxide 40 MG/ML / Magnesium Hydroxide 40 MG/ML / Simethicone 4 MG/ML Oral SuspensionAluminum Hydroxide 80 MG/ML / Magnesium Hydroxide 80 MG/ML / Simethicone 8 MG/ML Oral Suspension
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Broader (1)

Immunologic Adjuvants

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Aluminum Hydroxide
Immunologic Adjuvants
Aluminum Hydroxide 40 MG/ML / Magnesium Hydroxide 40 MG/ML / Simethicone 4 MG/ML Oral Suspension
Menthol 0.05 MG/MG Medicated Patch
magaldrate
chemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
DNA released from dying host cells mediates aluminum adjuvant activity
Aluminum-based adjuvants (aluminum salts or alum) are widely used in human vaccination, although their mechanisms of action are… (More)
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Highly Cited
2009
Highly Cited
2009
Aluminum hydroxide injections lead to motor deficits and motor neuron degeneration.
Gulf War Syndrome is a multi-system disorder afflicting many veterans of Western armies in the 1990-1991 Gulf War. A number of… (More)
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Highly Cited
2008
Highly Cited
2008
The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1beta secretion but dispensable for adjuvant activity.
Aluminum hydroxide (alum) is the most widely used adjuvant in human vaccines, but the immune mechanisms that are activated by… (More)
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Highly Cited
2008
Highly Cited
2008
The adjuvants aluminum hydroxide and MF59 induce monocyte and granulocyte chemoattractants and enhance monocyte differentiation toward dendritic cells.
Aluminum hydroxide (alum) and the oil-in-water emulsion MF59 are widely used, safe and effective adjuvants, yet their mechanism… (More)
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Highly Cited
2008
Highly Cited
2008
Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
Alum (aluminum hydroxide) is the most widely used adjuvant in human vaccines, but the mechanism of its adjuvanticity remains… (More)
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Highly Cited
2008
Highly Cited
2008
Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome.
Adjuvants are vaccine additives that stimulate the immune system without having any specific antigenic effect of itself. In this… (More)
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Highly Cited
2007
Highly Cited
2007
Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release.
Aluminum hydroxide (Alum) is the only adjuvant approved for routine use in humans, although the basis for its adjuvanticity… (More)
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Highly Cited
2005
Highly Cited
2005
Role of aluminum-containing adjuvants in antigen internalization by dendritic cells in vitro.
An important step in the induction of an immune response to vaccines is the internalization of antigens by antigen presenting… (More)
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Highly Cited
2004
Highly Cited
2004
T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node.
Dendritic cells (DCs) ingest antigens in peripheral tissues and migrate to lymph nodes where they present MHC class II-bound… (More)
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Highly Cited
1999
Highly Cited
1999
Osteoblast adhesion on nanophase ceramics.
Osteoblast adhesion on nanophase alumina (Al2O3) and titania (TiO2) was investigated in vitro. Osteoblast adhesion to nanophase… (More)
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