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Alkaline phosphatase isoenzyme, bone fraction

Known as: BSAP, bALP, alkaline phosphatase bone 
An isoform of alkaline phosphatase found on the surface of osteoblasts. The level of this enzyme in a patient's serum is proportional to the amount… 
National Institutes of Health

Related topics

Related topics

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Bone Specific Alkaline Phosphatase Measurement

Papers overview

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Highly Cited
2011
Highly Cited
2011
Single‐dose, placebo‐controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
Sclerostin, an osteocyte‐secreted protein, negatively regulates osteoblasts and inhibits bone formation. In this first‐in‐human… 
Highly Cited
2005
Highly Cited
2005
Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid.
PURPOSE Three large, randomized trials of patients with bone metastases recently demonstrated that zoledronic acid reduces the… 
Highly Cited
2005
Highly Cited
2005
Bap-dependent biofilm formation by pathogenic species of Staphylococcus: evidence of horizontal gene transfer?
The biofilm-associated protein (Bap) is a surface protein implicated in biofilm formation by Staphylococcus aureus isolated from… 
Highly Cited
2002
Highly Cited
2002
Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial.
The aim of the strontium ranelate (SR) for treatment of osteoporosis (STRATOS) trial was to investigate the efficacy and safety… 
Highly Cited
2001
Highly Cited
2001
Bap, a Staphylococcus aureus Surface Protein Involved in Biofilm Formation
ABSTRACT Identification of new genes involved in biofilm formation is needed to understand the molecular basis of strain… 
Highly Cited
2000
Highly Cited
2000
Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women.
BACKGROUND No published studies have directly examined the effect of soy protein with isoflavones on bone or bone turnover in… 
Highly Cited
1996
Highly Cited
1996
Healthy elderly French women living at home have secondary hyperparathyroidism and high bone turnover in winter. EPIDOS Study Group.
It was recently demonstrated that calcium and vitamin D supplements were capable of decreasing the incidence of hip fractures in… 
Highly Cited
1995
Highly Cited
1995
DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5)
Pax-6 is known to be a key regulator of vertebrate eye development. We have now isolated cDNA for an invertebrate Pax-6 protein… 
Highly Cited
1993
Highly Cited
1993
DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.
Previous DNA-binding studies indicated that an intact paired domain is required for interaction of the transcription factor BSAP… 
Highly Cited
1992
Highly Cited
1992
The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP
The CD19 protein is expressed on the surface of all B-lymphoid cells with the exception of terminally differentiated plasma cells… 
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