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Alkaline Ceramidase 1

Known as: ACER1, EC 3.5.1.23, N-Acylsphingosine Amidohydrolase 3 
Alkaline ceramidase 1 (264 aa, ~31 kDa) is encoded by the human ACER1 gene. This protein is involved in the catabolism of sphingolipid ceramides.
National Institutes of Health

Related topics

Related topics

7 relations
ACER1 geneEnzyme GeneHydrolysisLipid Metabolism

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
New fluorogenic probes for neutral and alkaline ceramidases[S]
New fluorogenic ceramidase substrates derived from the N-acyl modification of our previously reported probes (RBM14) are reported… 
2017
2017
Alkaline Ceramidase 1 Protects Mice from Premature Hair Loss by Maintaining the Homeostasis of Hair Follicle Stem Cells
2010
2010
Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes
Plasma sphingosine‐1‐phosphate (S1P) has been suggested to mainly originate from erythrocytes; however, within the erythrocyte… 
Review
2008
Review
2008
Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate.
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