Alexander Disease

Known as: Leukodystrophy with Rosenthal Fibers, Fibrinoid Degeneration of Astrocytes, Alexander's Disease 
Rare leukoencephalopathy with infantile-onset accumulation of Rosenthal fibers in the subpial, periventricular, and subependymal zones of the brain… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Glial fibrillary acidic protein (GFAP) is the principle intermediate filament (IF) protein in astrocytes. Mutations in the GFAP… (More)
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Highly Cited
2007
Highly Cited
2007
Comprehensive knowledge of the genomic alterations that underlie cancer is a critical foundation for diagnostics, prognostics… (More)
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Highly Cited
2005
Highly Cited
2005
Alexander disease is a progressive, usually fatal neurological disorder defined by the widespread and abundant presence in… (More)
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Highly Cited
2005
Highly Cited
2005
The purpose of this study was to describe unusual variants of Alexander's disease. We studied 10 patients who did not meet… (More)
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Review
2002
Review
2002
Alexander disease is a rare but often fatal disease of the central nervous system. Infantile, juvenile and adult forms have been… (More)
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Highly Cited
2001
Highly Cited
2001
Alexander disease is a rare disorder of the central nervous system of unknown etiology. Infants with Alexander disease develop a… (More)
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Highly Cited
1989
Highly Cited
1989
Rosenthal fibers (RFs) are abnormal inclusions within astrocytes, characteristic of Alexander's disease. We have previously… (More)
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1985
1985
Alexander's disease is a rare and poorly understood cause of progressive neurological deterioration. Although the clinical… (More)
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Highly Cited
1982
Highly Cited
1982
Placenta malarial changes (PMCs) related to maternal plasmodium infection were present in 33% (247 cases) of a series of 741… (More)
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1976
1976
A boy with juvenile onset of symptoms of Alexander's disease had a clinical picture of pseudobulbar palsy, ataxia, and spastic… (More)
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