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Alcaligenaceae bacterium FB188

Known as: Alcaligenes sp. (strain DSM 11172), Bordetella sp. (strain FB188), Bordetella/Alcaligenes strain FB188 (DSM 11172) 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2008
01220042008

Papers overview

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2008
2008
Identification of novel small-molecule histone deacetylase inhibitors by medium-throughput screening using a fluorigenic assay.
HDACs (histone deacetylases) are considered to be among the most important enzymes that regulate gene expression in eukaryotic… (More)
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2007
2007
Complex structure of a bacterial class 2 histone deacetylase homologue with a trifluoromethylketone inhibitor.
Histone deacetylases (HDACs) have emerged as attractive targets in anticancer drug development. To date, a number of HDAC… (More)
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2007
2007
An active site tyrosine residue is essential for amidohydrolase but not for esterase activity of a class 2 histone deacetylase-like bacterial enzyme.
HDACs (histone deacetylases) are considered to be among the most important enzymes that regulate gene expression in eukaryotic… (More)
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2006
2006
Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases.
Histone deacetylases (HDACs) are key enzymes in the transcriptional regulation of gene expression in eukaryotic cells. In recent… (More)
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2005
2005
Crystal structure of a bacterial class 2 histone deacetylase homologue.
Histone deacetylases (HDACs) are among the most promising targets in cancer therapy. However, structural information greatly… (More)
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2004
2004
Members of the histone deacetylase superfamily differ in substrate specificity towards small synthetic substrates.
Histone deacetylases (HDACs) are important enzymes for the transcriptional regulation of gene expression in eukaryotic cells… (More)
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2004
2004
A new amidohydrolase from Bordetella or Alcaligenes strain FB188 with similarities to histone deacetylases.
The full-length gene encoding the histone deacetylase (HDAC)-like amidohydrolase (HDAH) from Bordetella or Alcaligenes… (More)
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