Akita

The Akita is a powerful, solid, well-proportioned and distinctive looking dog. This breed is strong and muscular with a flat, heavy head and strong… (More)
National Institutes of Health

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Highly Cited
2014
Highly Cited
2014
Our previous work has shown that gene knockout of the sodium-glucose cotransporter SGLT2 modestly lowered blood glucose in… (More)
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2013
2013
Diabetic cardiomyopathy is a leading cause of morbidity and mortality, and Insulin2 mutant (Ins2+/−) Akita is a genetic mice… (More)
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2009
2009
Diabetic autonomic neuropathy is a debilitating, poorly studied complication of diabetes. Our previous studies of non-obese… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Fatty acid-induced mitochondrial uncoupling and oxidative stress have been proposed to reduce cardiac efficiency and… (More)
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2008
2008
Multidrug resistance (MDR) seriously limits the efficacy of chemotherapy in patients with cancer and leukemia. Active transport… (More)
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2006
2006
The role of polymorphonuclear neutrophils (PMN) in mediating diabetic tissue damage to the periodontium was investigated in a… (More)
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Highly Cited
2003
Highly Cited
2003
Autosomal dominant diabetes in the Akita mouse is caused by mutation of the insulin 2 gene, whose product replaces a cysteine… (More)
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Review
2002
Review
2002
  • David Ron
  • The Journal of clinical investigation
  • 2002
Mutations that impair polypeptide folding commonly result in an unstable and hypofunctional gene product. Their phenotype… (More)
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Highly Cited
2001
Highly Cited
2001
Resistance of the twospotted spider mite, Tetranychus urticae Koch, to acaricides acting as mitochondrial electron transport… (More)
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1987
1987
An analysis was performed of 2,168 consecutive stroke patients who were examined by computed tomography and entered into a… (More)
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