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Aglatimagene Besadenovec

Known as: ADV-tk, Virafir 
An adenoviral vector engineered to express the herpes simplex virus thymidine kinase (HSV-tk) gene, which, when administered in conjunction with a… 
National Institutes of Health

Papers overview

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2018
2018
Phase I Study of Intrapleural Gene-Mediated Cytotoxic Immunotherapy in Patients with Malignant Pleural Effusion.
2016
2016
Abstract CT110: Phase II multicenter study of gene-mediated cytotoxic immunotherapy as an adjuvant to surgical resection for newly diagnosed malignant glioma: lessons learned from pseudo-progression…
Gene Mediated Cytotoxic Immunotherapy (GMCI) generates a polyvalent anti-tumor immune response via local delivery of aglatimagene… 
2015
2015
Gene-mediated cytotoxic immunotherapy as adjuvant to surgery or chemoradiation for pancreatic adenocarcinoma
AbstractBackground While surgical resection of pancreatic adenocarcinoma provides the only chance of cure, long-term survival… 
2015
2015
Phase II multicenter study of gene mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma.
2010 Background: New therapies are desperately needed for malignant gliomas since aggressive standard of care (SOC) treatment… 
1995
1995
Adenovirus-mediated gene therapy in an experimental model of breast cancer metastatic to the brain.
We investigated the therapeutic efficacy of adenovirus-mediated gene therapy to treat malignant mammary tumors in vitro and in… 
1995
1995
Adenovirus-mediated gene therapy for experimental spinal cord tumors: tumoricidal efficacy and functional outcome
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