Aglatimagene Besadenovec

Known as: ADV-tk, Virafir 
An adenoviral vector engineered to express the herpes simplex virus thymidine kinase (HSV-tk) gene, which, when administered in conjunction with a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2018
0119942018

Papers overview

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2018
2018
Gene-mediated cytotoxic immunotherapy (GMCI) is an immune strategy implemented through local delivery of an adenovirus-based… (More)
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2016
2016
BACKGROUND Despite aggressive standard of care (SOC) treatment, survival of malignant gliomas remains very poor. This Phase II… (More)
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2015
2015
While surgical resection of pancreatic adenocarcinoma provides the only chance of cure, long-term survival remains poor… (More)
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1995
1995
We evaluated the efficacy of adenoviral-mediated gene therapy of experimental spinal cord tumors and the functional outcome after… (More)
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1995
1995
BACKGROUND Vascular smooth muscle cell (VSMC) proliferation following arterial injury plays a critical role in a variety of… (More)
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1995
1995
We investigated the therapeutic efficacy of adenovirus-mediated gene therapy to treat malignant mammary tumors in vitro and in… (More)
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1994
1994
The efficacy of adenovirus (ADV)-mediated gene therapy to treat brain tumors was tested in a syngeneic glioma model. Tumor cells… (More)
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