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Aglatimagene Besadenovec

Known as: ADV-tk, Virafir 
An adenoviral vector engineered to express the herpes simplex virus thymidine kinase (HSV-tk) gene, which, when administered in conjunction with a… Expand
National Institutes of Health

Papers overview

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2018
2018
Gene-mediated cytotoxic immunotherapy (GMCI) is an immune strategy implemented through local delivery of an adenovirus-based… Expand
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2016
2016
BACKGROUND Despite aggressive standard of care (SOC) treatment, survival of malignant gliomas remains very poor. This Phase II… Expand
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2016
2016
BACKGROUND Gene-mediated cytotoxic immunotherapy (GMCI) is a tumor-specific immune stimulatory strategy implemented through local… Expand
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2016
2016
Gene Mediated Cytotoxic Immunotherapy (GMCI) generates a polyvalent anti-tumor immune response via local delivery of aglatimagene… Expand
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2015
2015
AbstractBackground While surgical resection of pancreatic adenocarcinoma provides the only chance of cure, long-term survival… Expand
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2015
2015
2010 Background: New therapies are desperately needed for malignant gliomas since aggressive standard of care (SOC) treatment… Expand
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1995
1995
We evaluated the efficacy of adenoviral-mediated gene therapy of experimental spinal cord tumors and the functional outcome after… Expand
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1995
1995
We investigated the therapeutic efficacy of adenovirus-mediated gene therapy to treat malignant mammary tumors in vitro and in… Expand
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