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Aglatimagene Besadenovec

Known as: ADV-tk, Virafir 
An adenoviral vector engineered to express the herpes simplex virus thymidine kinase (HSV-tk) gene, which, when administered in conjunction with a… 
National Institutes of Health

Papers overview

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2016
2016
BACKGROUND Gene-mediated cytotoxic immunotherapy (GMCI) is a tumor-specific immune stimulatory strategy implemented through local… 
2016
2016
Gene Mediated Cytotoxic Immunotherapy (GMCI) generates a polyvalent anti-tumor immune response via local delivery of aglatimagene… 
Highly Cited
2015
Highly Cited
2015
BACKGROUND Despite aggressive standard of care (SOC) treatment, survival of malignant gliomas remains very poor. This Phase II… 
2015
2015
AbstractBackground While surgical resection of pancreatic adenocarcinoma provides the only chance of cure, long-term survival… 
1995
1995
We investigated the therapeutic efficacy of adenovirus-mediated gene therapy to treat malignant mammary tumors in vitro and in…