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Aes-103

 
National Institutes of Health

Papers overview

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Review
2014
Review
2014
  • M. Safo, G. Kato
  • Hematology/oncology clinics of North America
  • 2014
  • Corpus ID: 9014903
The pathophysiology of sickle cell disease involves the polymerization of sickle hemoglobin in its T state, which develops under… Expand
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2014
2014
In preclinical and early phase pharmacologic trials in sickle cell disease, the percentage of sickled erythrocytes after… Expand
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2014
2014
Background: Under hypoxic conditions, sickle hemoglobin (HbS) polymerizes, causing morphologic distortion (sickling) of red blood… Expand
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Review
2013
Review
2013
Background Aes-103 (5-hydroxymethylfurfural, 5-HMF) is a putative anti-sickling agent that has undergone pre-clinical testing for… Expand
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2012
2012
Abstract 3210 5-HMF (5-hydroxymethyl-2-furfural; Aes-103) is a breakdown product of glucose that has potent anti-sickling… Expand
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