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Aes-103
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
The pathophysiology of sickle cell disease involves the polymerization of sickle hemoglobin in its T state, which develops under… Expand
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2014
2014
In preclinical and early phase pharmacologic trials in sickle cell disease, the percentage of sickled erythrocytes after… Expand
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2014
2014
Background: Under hypoxic conditions, sickle hemoglobin (HbS) polymerizes, causing morphologic distortion (sickling) of red blood… Expand
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Review
2013
Review
2013
Background Aes-103 (5-hydroxymethylfurfural, 5-HMF) is a putative anti-sickling agent that has undergone pre-clinical testing for… Expand
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2012
2012
Abstract 3210 5-HMF (5-hydroxymethyl-2-furfural; Aes-103) is a breakdown product of glucose that has potent anti-sickling… Expand
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