Adenylate Cyclase Toxin

Known as: Bordetella Ac-Hly, AC Toxin, Bordetella, Toxin, Bordetella AC 
One of the virulence factors produced by virulent BORDETELLA organisms. It is a bifunctional protein with both ADENYLYL CYCLASES and hemolysin… (More)
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Pertussis toxin and adenylate cyclase toxin are two important virulence factors of Bordetella pertussis, the bacterial cause of… (More)
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Highly Cited
2010
Highly Cited
2010
Inflammasome-mediated IL-1beta production is central to the innate immune defects that give rise to certain autoinflammatory… (More)
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Review
2006
Review
2006
Bordetella that infect mammals produce a multifunctional repeat in toxin (RTX) adenylate cyclase toxin known as CyaA, an… (More)
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Highly Cited
2004
Highly Cited
2004
Adenylate cyclase toxin (CyaA) from Bordetella pertussis can subvert host immune responses allowing bacterial colonization. Here… (More)
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Highly Cited
1994
Highly Cited
1994
A number of bacterial protein toxins, including adenylate cyclase (AC) toxin from Bordetella pertussis, require the product of an… (More)
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Highly Cited
1993
Highly Cited
1993
The adenylate cyclase toxin of Bordetella pertussis is a secreted multifunctional protein, endowed with calmodulin-activated… (More)
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Highly Cited
1993
Highly Cited
1993
Bordetella pertussis, the causative agent of whooping cough, has been shown recently to enter and survive in epithelial cells and… (More)
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1991
1991
Adenylate cyclase (AC) toxin from B. pertussis enters eukaryotic cells where it produces supraphysiologic levels of cAMP… (More)
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Highly Cited
1988
Highly Cited
1988
Bordetella pertussis and Bacillus anthracis produce extracytoplasmic adenylate cyclase toxins (AC toxins) with shared features… (More)
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Highly Cited
1988
Highly Cited
1988
The calmodulin-sensitive adenylate cyclase of Bordetella pertussis, a 45 kd secreted protein, is synthesized as a 1706 amino acid… (More)
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