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Adenylate Cyclase Toxin

Known as: Bordetella Ac-Hly, AC Toxin, Bordetella, Toxin, Bordetella AC 
One of the virulence factors produced by virulent BORDETELLA organisms. It is a bifunctional protein with both ADENYLYL CYCLASES and hemolysin… Expand
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Pertussis toxin and adenylate cyclase toxin are two important virulence factors of Bordetella pertussis, the bacterial cause of… Expand
Highly Cited
2010
Highly Cited
2010
Inflammasome-mediated IL-1β production is central to the innate immune defects that give rise to certain autoinflammatory… Expand
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Review
2006
Review
2006
Bordetella that infect mammals produce a multifunctional repeat in toxin (RTX) adenylate cyclase toxin known as CyaA, an… Expand
Highly Cited
2005
Highly Cited
2005
ABSTRACT Previously we found that pertussis toxin (PT), an exotoxin virulence factor produced by Bordetella pertussis, plays an… Expand
Highly Cited
2001
Highly Cited
2001
The adenylate cyclase toxin (CyaA) of Bordetella pertussis is a major virulence factor required for the early phases of lung… Expand
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Highly Cited
1998
Highly Cited
1998
Enteropathogenic Escherichia coli (EPEC) causes diarrhoea in young children. EPEC induces the formation of actin pedestal in… Expand
Highly Cited
1995
Highly Cited
1995
The adenylate cyclase (CyaA) secreted by Bordetella pertussis is a toxin that is able to enter eukaryotic cells and cause a… Expand
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Highly Cited
1994
Highly Cited
1994
A number of bacterial protein toxins, including adenylate cyclase (AC) toxin from Bordetella pertussis, require the product of an… Expand
Highly Cited
1993
Highly Cited
1993
Bordetella pertussis, the causative agent of whooping cough, has been shown recently to enter and survive in epithelial cells and… Expand
Highly Cited
1988
Highly Cited
1988
The calmodulin‐sensitive adenylate cyclase of Bordetella pertussis, a 45 kd secreted protein, is synthesized as a 1706 amino acid… Expand