Adatanserin Hydrochloride

National Institutes of Health

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2020

2020

Synthesis and biological evaluation of thioadatanserin and its dialkylated products as partial 5-HTR1A agonists and 5-HTR2A antagonists for potential use in depression and anxiety disorders.

C. Evans, Andrea Zuluaga, Diego Vasquez Matute, Sarah Baradaran-Noviri, Natalia Perez-Cervantes, M. Siegler
Bioorganic & medicinal chemistry letters
2020

Corpus ID: 220384583

Thionation of adatanserin hydrochloride (2) with Lawesson's reagent in toluene/triethylamine afforded novel compound, (3r,5r,7r… Expand