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Adaptive Design
Known as:
ADAPT
A study design which includes a prospectively planned opportunity for modification of one or more specified aspects of the study design and/or…
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National Institutes of Health
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CDISC SDTM Trial Summary Parameter Terminology by Code
CDISC SDTM Trial Summary Parameter Terminology by Name
Clinical Data Interchange Standards Consortium Terminology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Early phase and adaptive design clinical trials in rheumatoid arthritis: a systematic review of early phase trials
Tim Pickles
,
R. Christensen
,
L. Tam
,
L. Simon
,
E. Choy
Rheumatology Advances in Practice
2018
Corpus ID: 80851767
Abstract Objective Adaptive designs can enable highly sophisticated and efficient early phase trials, but the clinical inference…
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Review
2017
Review
2017
LUME-Meso: Design and Rationale of the Phase III Part of a Placebo-Controlled Study of Nintedanib and Pemetrexed/Cisplatin Followed by Maintenance Nintedanib in Patients With Unresectable Malignant…
G. Scagliotti
,
R. Gaafar
,
+9 authors
S. Popat
Clinical Lung Cancer
2017
Corpus ID: 206816786
Review
2017
Review
2017
DIA’s Adaptive Design Scientific Working Group (ADSWG): Best Practices Case Studies for “Less Well-understood” Adaptive Designs
E. Miller
,
P. Gallo
,
+9 authors
Y. Jemiai
Therapeutic Innovation and Regulatory Science
2017
Corpus ID: 52308576
Adaptive design (AD) clinical trials use accumulating subject data to modify the parameters of the design of an ongoing study…
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2016
2016
Seamless Phase IIa/IIb and enhanced dose-finding adaptive design
Jiacheng Yuan
,
H. Pang
,
T. Tong
,
Dong Xi
,
Wenzhao Guo
,
P. Mesenbrink
Journal of Biopharmaceutical Statistics
2016
Corpus ID: 29993441
ABSTRACT In drug development, when the drug class has a relatively well-defined path to regulatory approval and the enrollment is…
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2012
2012
A Bayesian adaptive design for multi-dose, randomized, placebo-controlled phase I/II trials.
Fang Xie
,
Yuan Ji
,
L. Tremmel
Contemporary Clinical Trials
2012
Corpus ID: 16407598
2011
2011
Optimization of UWB planar antennas using adaptive design specifications
S. Ogurtsov
,
S. Koziel
European Conference on Antennas and Propagation
2011
Corpus ID: 34953567
A simulation-driven optimization framework for computationally efficient design of ultrawideband (UWB) antennas is presented. Our…
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2010
2010
Impacts on type I error rate with inappropriate use of learn and confirm in confirmatory adaptive design trials
Sue-Jane Wang
,
H. J. James Hung
,
R. O'neill
Biometrical journal. Biometrische Zeitschrift
2010
Corpus ID: 205478948
A two‐stage adaptive design trial is a single trial that combines the learning data from stage 1 (or phase II) and the confirming…
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2006
2006
Product adaptive design based on extension co-transforming: a differential approach
Su Nan
,
Zhao Yanwei
,
Guo Mingfei
,
Tan Huijun
7th International Conference on Computer-Aided…
2006
Corpus ID: 45421989
The concept of adaptable design (AD) immensely influences the suitability of a product life-cycle (PLC).The product with more…
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2005
2005
A Hybrid Bayesian Adaptive Design for Dose Response Trials
Mark Chang
,
S. Chow
Journal of Biopharmaceutical Statistics
2005
Corpus ID: 8290293
ABSTRACT In recent years, the use of adaptive design methods based on accrued data of on-going trials have become very popular…
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2000
2000
Analysis of time trends in adaptive designs with application to a neurophysiology experiment.
Feifang Hu
,
William F. Rosenberger
,
William F. Rosenberger
Statistics in Medicine
2000
Corpus ID: 44343894
Time trends are present in many sequential experiments. Adaptive designs use accruing data to select future design points. It has…
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