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Adaptive Design

Known as: ADAPT 
A study design which includes a prospectively planned opportunity for modification of one or more specified aspects of the study design and/or… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
We compare several adaptive design strategies using a data set of 223 M2AX family of compounds for which the elastic properties… Expand
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2016
2016
Simon's optimal two-stage design has been widely used in early phase clinical trials for Oncology and AIDS studies with binary… Expand
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Highly Cited
2015
Highly Cited
2015
In this paper, a new adaptive design method is proposed for reaction force observer (RFOB)-based robust force control systems. It… Expand
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2014
2014
Dose-finding studies in non-oncology areas are usually conducted in Phase II of the development process of a new potential… Expand
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2013
2013
Probability weighting functions relate objective probabilities and their subjective weights, and play a central role in modeling… Expand
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2011
2011
A critical challenge in the development of new molecularly targeted anticancer drugs is the identification of predictive… Expand
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Review
2009
Review
2009
In this article, we present a discussion of two general ways in which the traditional randomized trial can be modified or adapted… Expand
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2005
2005
Abstract In long-term clinical trials we often need to monitor the patients’ enrollment, compliance, and treatment effect during… Expand
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2005
2005
  • M. Chang, S. Chow
  • Journal of biopharmaceutical statistics
  • 2005
  • Corpus ID: 8290293
ABSTRACT In recent years, the use of adaptive design methods based on accrued data of on-going trials have become very popular… Expand
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Highly Cited
2001
Highly Cited
2001
Proschan and Hunsberger (1995, Biometrics 51, 1315-1324) proposed a two-stage adaptive design that maintains the Type I error… Expand
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