Skip to search formSkip to main contentSkip to account menu

Adaptive Design

Known as: ADAPT 
A study design which includes a prospectively planned opportunity for modification of one or more specified aspects of the study design and/or… 
National Institutes of Health

Related topics

Related topics

3 relations
CDISC SDTM Trial Summary Parameter Terminology by CodeCDISC SDTM Trial Summary Parameter Terminology by NameClinical Data Interchange Standards Consortium Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Early phase and adaptive design clinical trials in rheumatoid arthritis: a systematic review of early phase trials
Abstract Objective Adaptive designs can enable highly sophisticated and efficient early phase trials, but the clinical inference… 
Review
2017
Review
2017
LUME-Meso: Design and Rationale of the Phase III Part of a Placebo-Controlled Study of Nintedanib and Pemetrexed/Cisplatin Followed by Maintenance Nintedanib in Patients With Unresectable Malignant…
Review
2017
Review
2017
DIA’s Adaptive Design Scientific Working Group (ADSWG): Best Practices Case Studies for “Less Well-understood” Adaptive Designs
Adaptive design (AD) clinical trials use accumulating subject data to modify the parameters of the design of an ongoing study… 
2016
2016
Seamless Phase IIa/IIb and enhanced dose-finding adaptive design
ABSTRACT In drug development, when the drug class has a relatively well-defined path to regulatory approval and the enrollment is… 
2012
2012
A Bayesian adaptive design for multi-dose, randomized, placebo-controlled phase I/II trials.
2011
2011
Optimization of UWB planar antennas using adaptive design specifications
A simulation-driven optimization framework for computationally efficient design of ultrawideband (UWB) antennas is presented. Our… 
2010
2010
Impacts on type I error rate with inappropriate use of learn and confirm in confirmatory adaptive design trials
A two‐stage adaptive design trial is a single trial that combines the learning data from stage 1 (or phase II) and the confirming… 
2006
2006
Product adaptive design based on extension co-transforming: a differential approach
The concept of adaptable design (AD) immensely influences the suitability of a product life-cycle (PLC).The product with more… 
2005
2005
A Hybrid Bayesian Adaptive Design for Dose Response Trials
ABSTRACT In recent years, the use of adaptive design methods based on accrued data of on-going trials have become very popular… 
2000
2000
Analysis of time trends in adaptive designs with application to a neurophysiology experiment.
Time trends are present in many sequential experiments. Adaptive designs use accruing data to select future design points. It has… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)