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AcrAB-TolC complex

Known as: AcrAB-TolC complex location 
National Institutes of Health

Papers overview

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2018
2018
Upregulation of AcrEF in Quinolone Resistance Development in Escherichia coli When AcrAB-TolC Function Is Impaired.
We studied mechanisms of drug resistance development in Escherichia coli strains lacking efflux pump components. E. coli K12… 
2017
2017
Design and Selection of a Synthetic Feedback Loop for Optimizing Biofuel Tolerance.
Feedback control allows cells to dynamically sense and respond to environmental changes. However, synthetic controller designs… 
2017
2017
Contribution of AcrAB-TolC to multidrug resistance in an Escherichia coli sequence type 131 isolate.
2014
2014
AraC/XylS Family Stress Response Regulators Rob, SoxS, PliA, and OpiA in the Fire Blight Pathogen Erwinia amylovora
ABSTRACT Transcriptional regulators of the AraC/XylS family have been associated with multidrug resistance, organic solvent… 
2012
2012
Total Alkaloids of Sophorea alopecuroides‐induced Down‐regulation of AcrAB‐ToLC Efflux Pump Reverses Susceptibility to Ciprofloxacin in Clinical Multidrug Resistant Escherichia coli isolates
In this report, total alkaloids extracted from the seeds of Sophorea alopecuroides (TASA) was evaluated against clinical… 
Highly Cited
2010
Highly Cited
2010
Substrate path in the AcrB multidrug efflux pump of Escherichia coli
A major tripartite multidrug efflux pump of Escherichia coli, AcrAB–TolC, confers resistance to a wide variety of compounds. The… 
Highly Cited
2010
Highly Cited
2010
Kinetic Parameters of Efflux of Penicillins by the Multidrug Efflux Transporter AcrAB-TolC of Escherichia coli
ABSTRACT The multidrug efflux transporter AcrAB-TolC is known to pump out a diverse range of antibiotics, including β-lactams… 
2009
2009
Periplasmic adaptor protein AcrA has a distinct role in the antibiotic resistance and virulence of Salmonella enterica serovar Typhimurium.
OBJECTIVES AcrA can function as the periplasmic adaptor protein (PAP) in several RND tripartite efflux pumps, of which AcrAB-TolC… 
2007
2007
Molecular Cloning and Characterization of All RND‐Type Efflux Transporters in Vibrio cholerae Non‐O1
Resistance Nodulation cell Division (RND) efflux transporters are thought to be involved in mediating multidrug resistance in… 
2007
2007
Reduced Susceptibility of Haemophilus influenzae to the Peptide Deformylase Inhibitor LBM415 Can Result from Target Protein Overexpression Due to Amplified Chromosomal def Gene Copy Number
ABSTRACT Previous genetic analysis of Haemophilus influenzae revealed two mechanisms associated with decreased susceptibility to… 
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