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AZD3582

Known as: AZD 3582, AZD-3582 
National Institutes of Health

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Related topics

2 relations
HCT 3012Naproxcinod

Papers overview

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Review
2009
Review
2009
Naproxcinod, a new cyclooxygenase-inhibiting nitric oxide donator (CINOD)
Background: COX-inhibiting nitric oxide donators (CINODs) are a new class of drugs that combine the actions of the parent COX… 
Review
2009
Review
2009
Naproxcinod, a new cyclooxygenase-inhibiting nitric oxide donator (CINOD).
BACKGROUND COX-inhibiting nitric oxide donators (CINODs) are a new class of drugs that combine the actions of the parent COX… 
2006
2006
Dose–effect comparisons of the CINOD AZD3582 and naproxen on upper gastrointestinal tract mucosal injury in healthy subjects
Objective. The objective of this endoscopic study was to compare the effects on the gastroduodenal mucosa of healthy volunteers… 
2005
2005
Direct gas measurements indicate that the novel cyclooxygenase inhibitor AZD3582 is an effective nitric oxide donor in vivo
1 AZD3582 [4‐(nitrooxy)butyl‐(2S)‐2‐(6‐methoxy‐2‐naphthyl)propanoate] is a COX‐inhibiting nitric oxide donor that inhibits COX‐1… 
2005
2005
Pre-clinical pharmacokinetics of the cyclooxygenase-inhibiting nitric oxide donor (CINOD) AZD3582.
The pre-clinical pharmacokinetics of AZD3582 (4-(nitrooxy)butyl-(2S)-2-(6-methoxy-2-naphthyl) propanoate) and its primary… 
2005
2005
Pre‐clinical pharmacokinetics of the cyclooxygenase‐inhibiting nitric oxide donor (CINOD) AZD3582
The pre‐clinical pharmacokinetics of AZD3582 (4‐(nitrooxy)butyl‐(2S)‐2‐(6‐methoxy‐2‐naphthyl) propanoate) and its primary… 
2005
2005
Renal Effects of the Cyclooxygenase‐inhibiting Nitric Oxide Donator AZD3582 Compared with Rofecoxib and Naproxen During Normal and Low Sodium Intake
2004
2004
COX-inhibiting nitric oxide donators (CINODs) -- a new paradigm in the treatment of pain and inflammation
The clinical utility of non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for pain relief is tempered by their… 
Highly Cited
2003
Highly Cited
2003
Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans
Background: Cyclooxygenase inhibiting nitric oxide donators (CINODs) are a new class of anti-inflammatory and analgesic drugs… 
2003
2003
The CINOD, AZD3582, exhibits an improved gastrointestinal safety profile compared with naproxen in healthy volunteers
COX-inhibiting nitric oxide donators (CINODs) are a new class of drugs in development for the treatment of acute and chronic pain… 
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