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AZD1981

 
National Institutes of Health

Papers overview

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2019
2019
Background: Approximately 50% of patients with chronic spontaneous urticaria (CSU) experience symptoms that are not fully… Expand
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2018
2018
Objectives To evaluate the efficacy and safety of AZD1981, a potent, specific antagonist of the CRTh2 receptor, as add-on therapy… Expand
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2018
2018
Aims/Hypothesis GPR44 (DP2, PTGDR2, CRTh2) is the receptor for the pro-inflammatory mediator prostaglandin D2 (PGD2) and it is… Expand
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Review
2017
Review
2017
Prostaglandin D2 (PGD2) released by degranulating mast cells is believed to play a key role in orchestrating mechanisms of… Expand
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Review
2017
Review
2017
The introduction of omalizumab to the management of chronic spontaneous urticaria (CSU) has markedly improved the therapeutic… Expand
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2017
2017
AIM AZD1981 is an orally bioavailable chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTh2) receptor… Expand
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2016
2016
Background Chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cell (CRTh2) receptor antagonists is… Expand
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2013
2013
BACKGROUND AND PURPOSE The discovery of DP2 as a second receptor for PGD2 has prompted the search for antagonists as potential… Expand
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2013
2013
OBJECTIVE To evaluate the efficacy and tolerability of the selective CRTh2 (DP2) receptor antagonist AZD1981 compared with… Expand
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2011
2011
Novel indole-3-thio-, 3-sulfonyl- and 3-oxy-aryl-1-acetic acids are reported which are potent, selective antagonists of the… Expand
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