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AZD0865

 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

ImidazolesPyridines
linaprazan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Predictors of either rapid healing or refractory reflux oesophagitis during treatment with potent acid suppression
Little is known regarding patient characteristics that influence the speed of reflux oesophagitis (RO) healing. 
Highly Cited
2012
Highly Cited
2012
An In Vitro Methodology for Forecasting Luminal Concentrations and Precipitation of Highly Permeable Lipophilic Weak Bases in the Fasted Upper Small Intestine
PurposeTo develop an in vitro methodology for prediction of concentrations and potential precipitation of highly permeable… Expand
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Highly Cited
2012
Highly Cited
2012
Regurgitation is less responsive to acid suppression than heartburn in patients with gastroesophageal reflux disease.
BACKGROUND & AIMS Although most patients with gastroesophageal reflux disease (GERD) achieve substantial symptom relief with acid… Expand
2012
2012
Concomitant Symptoms Itemized in the Reflux Disease Questionnaire Are Associated With Attenuated Heartburn Response to Acid Suppression
OBJECTIVES:The Reflux Disease Questionnaire (RDQ) contains six symptom items for diagnosing and gauging gastroesophageal reflux… Expand
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Highly Cited
2010
Highly Cited
2010
Predicting Intestinal Precipitation—A Case Example for a Basic BCS Class II Drug
ABSTRACTPurposeTo investigate the prediction accuracy of in vitro and in vitro/in silico methods for in vivo intestinal… Expand
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Highly Cited
2008
Highly Cited
2008
A Randomized, Comparative Trial of a Potassium-Competitive Acid Blocker (AZD0865) and Esomeprazole for the Treatment of Patients With Nonerosive Reflux Disease
OBJECTIVES:AZD0865 is a gastric acid-suppressing agent that has a rapid onset of action and long duration of effect. This double… Expand
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Highly Cited
2007
Highly Cited
2007
A randomized, comparative study of three doses of AZD0865 and esomeprazole for healing of reflux esophagitis.
BACKGROUND & AIMS AZD0865 belongs to a new class of acid-suppressing agents with rapid onset of action and potent acid inhibition… Expand
2007
2007
Mechanism of action of AZD0865, a K+-competitive inhibitor of gastric H+,K+-ATPase.
AZD0865 is a member of a drug class that inhibits gastric H(+),K(+)-ATPase by K(+)-competitive binding. The objective of these… Expand
Review
2006
Review
2006
Acid Suppression Therapy: Where Do We Go from Here?
The dramatic success of pharmacological acid suppression in healing peptic ulcers and managing patients with gastroesophageal… Expand
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2006
2006
Characteristics of the K+-competitive H+,K+-ATPase inhibitor AZD0865 in isolated rat gastric glands.
The gastric H+,K+-ATPase of the parietal cell is responsible for acid secretion in the stomach and is the main target in the… Expand
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