ATR-ATRIP complex

Known as: ATR-ATRIP complex location 
A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is… (More)
National Institutes of Health

Papers overview

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2016
2016
The ataxia telangiectasia-mutated and Rad3-related (ATR) kinase checkpoint pathway maintains genome integrity; however, the role… (More)
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2016
2016
OBJECTIVE SUMOylation plays critical roles in a variety of physiological and pathological processes including tumorigenesis… (More)
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Highly Cited
2011
Highly Cited
2011
The ataxia telangiectasia-mutated and Rad3-related (ATR) kinase is a master checkpoint regulator safeguarding the genome. Upon… (More)
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Highly Cited
2010
Highly Cited
2010
ATR kinase is a critical upstream regulator of the checkpoint response to various forms of DNA damage. Previous studies have… (More)
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2009
2009
The activation of ATR-ATRIP in response to double-stranded DNA breaks (DSBs) depends upon ATM in human cells and Xenopus egg… (More)
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Highly Cited
2006
Highly Cited
2006
ATR is a key regulator of checkpoint responses to incompletely replicated and damaged DNA, but the mechanisms underlying control… (More)
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Highly Cited
2005
Highly Cited
2005
The Timeless protein is essential for circadian rhythm in Drosophila. The Timeless orthologue in mice is essential for viability… (More)
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Highly Cited
2004
Highly Cited
2004
Claspin is necessary for the ATR-dependent activation of Chk1 in Xenopus egg extracts containing incompletely replicated DNA. ATR… (More)
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2004
2004
The function of the ATR (ataxia-telangiectasia mutated and Rad3-related)-ATRIP (ATR-interacting protein) protein kinase complex… (More)
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Highly Cited
2003
Highly Cited
2003
The function of the ATR (ataxia-telangiectasia mutated- and Rad3-related)-ATRIP (ATR-interacting protein) protein kinase complex… (More)
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