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Patients with classic congenital adrenal hyperplasia (CAH) often require supraphysiologic glucocorticoid doses to… Expand BackgroundCushing’s syndrome in humans shares many similarities with its counterpart in dogs in terms of etiology (pituitary… Expand Adrenocortical carcinoma (ACC) is a rare malignancy with a dismal outcome. Complete surgical resection remains the only… Expand To further the development of new agents for the treatment of adrenocortical carcinoma (ACC), we characterized the molecular and… Expand ATR-101 is a novel, oral drug candidate currently in development for the treatment of adrenocortical cancer. ATR-101 is a… Expand Adrenocortical carcinoma (ACC) generally has poor prognosis. Existing treatments provide limited benefit for most patients with… Expand Adrenocortical carcinoma (ACC) is a malignancy that harbors a significant risk of recurrence even after complete resection and… Expand TPS4585 Background: ATR-101 (Atterocor, Inc., Ann Arbor, MI, USA) is a selective inhibitor of ACAT1 (acyl coenzyme A:cholesterol… Expand Cette invention concerne une nouvelle forme medicamenteuse solide du chlorhydrate de N-(2,6-bis(1-methylethyl)phenyl)-N'-((1-(4… Expand