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ATI-5261

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2010-2014
0120102014

Related topics

Related topics

1 relation

Broader (1)

Peptides

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
ATI-5261
Peptides

Papers overview

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2015
2015
Novel Apo E-Derived ABCA1 Agonist Peptide (CS-6253) Promotes Reverse Cholesterol Transport and Induces Formation of preβ-1 HDL In Vitro
Apolipoprotein (apo) mimetic peptides replicate some aspects of HDL function. We have previously reported the effects of compound… (More)
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2014
2014
Apolipoprotein E derived HDL mimetic peptide ATI-5261 promotes nascent HDL formation and reverse cholesterol transport in vitro.
Modulation of the reverse cholesterol transport (RCT) pathway may provide a therapeutic target for the prevention and treatment… (More)
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2013
2013
Retention of α-helical structure by HDL mimetic peptide ATI-5261 upon extensive dilution represents an important determinant for stimulating ABCA1 cholesterol efflux with high efficiency.
ATI-5261 is a novel, single-helix peptide that stimulates cellular cholesterol efflux with high potency similar to native… (More)
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2012
2012
The positional specificity of EXXK motifs within an amphipathic α-helix dictates preferential lysine modification by acrolein: implications for the design of high-density lipoprotein mimetic peptides…
Despite the ability of acrolein to damage proteins, factors governing its reactivity with the ε-amino group of lysine are poorly… (More)
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2011
2011
HDL mimetic peptide ATI-5261 forms an oligomeric assembly in solution that dissociates to monomers upon dilution.
ATI-5261 is a 26-mer peptide that stimulates cellular cholesterol efflux with high potency. This peptide displays high aqueous… (More)
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2010
2010
A new HDL mimetic peptide that stimulates cellular cholesterol efflux with high efficiency greatly reduces atherosclerosis in mice.
Here, we report the creation of a single-helix peptide (ATI-5261) that stimulates cellular cholesterol efflux with K(m) molar… (More)
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