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ATF4 wt Allele

Known as: TXREB, TAXREB67, CREB-2 
Human ATF4 wild-type allele is located in the vicinity of 22q13.1 and is approximately 3 kb in length. This allele, which encodes cyclic AMP… 
National Institutes of Health

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Related topics

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Transcriptional Regulation

Papers overview

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Highly Cited
2011
Highly Cited
2011
Redistribution of DAT/α-Synuclein Complexes Visualized by “In Situ” Proximity Ligation Assay in Transgenic Mice Modelling Early Parkinson's Disease
Alpha-synuclein, the major component of Lewy bodies, is thought to play a central role in the onset of synaptic dysfunctions in… 
2010
2010
Signalling pathways associated with 5-HT6 receptors: relevance for cognitive effects.
A growing body of evidence supports the use of serotonin 5-HT6 receptor antagonists as a promising mechanism for treating… 
Highly Cited
2005
Highly Cited
2005
cAMP-response Elements in Aplysia creb1, creb2, and Ap-uch Promoters
The Aplysia genes encoding for cAMP-response element-binding protein 1 (CREB1), CREB2, and ubiquitin C-terminal hydrolase (Ap-uch… 
Highly Cited
2004
Highly Cited
2004
Hippocampal CREB1 but not CREB2 is decreased in aged rats with spatial memory impairments
Highly Cited
2000
Highly Cited
2000
Microphthalmia due to p53-mediated apoptosis of anterior lens epithelial cells in mice lacking the CREB-2 transcription factor.
CREB-2 (also called ATF4, TAXREB67, or C/ATF) is an evolutionarily conserved member of the CREB/ATF family of basic-leucine… 
Highly Cited
2000
Highly Cited
2000
Molecular Interactions Involved in the Transactivation of the Human T-Cell Leukemia Virus Type 1 Promoter Mediated by Tax and CREB-2 (ATF-4)
ABSTRACT The human T-cell leukemia virus type 1 (HTLV-1) Tax protein activates viral transcription through three 21-bp repeats… 
1996
1996
CREB-1 and CREB-2 immunoreactivity in the rat brain
1994
1994
Identification of a TXREB pseudogene (TXREBP) located between the genes for p55 (MPP1) and G6PD on Xq28.
A fibroblast cDNA library was screened by hybridization to a yeast artificial chromosome containing genomic sequences from human… 
Highly Cited
1992
Highly Cited
1992
Molecular cloning of human CREB-2: an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element.
The cAMP response element (CRE) is an octanucleotide motif (TGACGTCA) that mediates diverse transcriptional regulatory effects… 
Review
1991
Review
1991
Isolation and nucleotide sequence of a murine cDNA homologous to human activating transcription factor 4.
Members of the Jun, Fos and ATF/CREB families constitute a super-family of b-zip DNA binding proteins capable of… 
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