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AT7519

Known as: AT 7519, AT-7519, AT7519M 
National Institutes of Health

Papers overview

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2020
2020
Background The poor outcomes in nasopharyngeal carcinoma (NPC) necessitate new treatments. AT7519 is a potent inhibitor of… 
2018
2018
Cyclin-dependent kinases (CDK) are considered to be potential targets of anticancer drugs that can interrupt the uncontrolled… 
2016
2016
Acute respiratory distress syndrome (ARDS) is a neutrophil-dominant disorder with no effective pharmacological therapies. While… 
Highly Cited
2015
Highly Cited
2015
Purpose: MYCN-dependent neuroblastomas have low cure rates with current multimodal treatment regimens and novel therapeutic drugs… 
2015
2015
Human male germ cell-associated kinase (hMAK) is an androgen-inducible gene in prostate epithelial cells, and it acts as a… 
Review
2009
Review
2009
Cyclin-dependent kinases (CDK), and their regulatory cyclin partners, play a central role in eukaryotic cell growth, division… 
2008
2008
Cyclin dependent kinases (CDKs) and their cyclin complexes play a crucial role in cell cycle control and transcriptional… 
2008
2008
3533 Background: AT7519M is a structure-based rationally designed Nan molar small molecular Cyclin-dependent Kinase (CDK… 
2007
2007
Cyclin Dependent Kinases (CDKs) play a central role in the eukaryotic cell cycle. The activation of these kinases is modulated by…