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ASTL gene

Known as: SAS1B, astacin-like metallo-endopeptidase (M12 family), OVASTACIN 
National Institutes of Health

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Broader (1)

Genes

Papers overview

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Highly Cited
2017
Highly Cited
2017
Melatonin improves the fertilization ability of post-ovulatory aged mouse oocytes by stabilizing ovastacin and Juno to promote sperm binding and fusion
STUDY QUESTION What are the underlying mechanisms of the decline in the fertilization ability of post-ovulatory aged oocytes… 
2017
2017
A Unique Egg Cortical Granule Localization Motif Is Required for Ovastacin Sequestration to Prevent Premature ZP2 Cleavage and Ensure Female Fertility in Mice
Monospermic fertilization is mediated by the extracellular zona pellucida composed of ZP1, ZP2 and ZP3. Sperm bind to the N… 
Review
2014
Review
2014
Thyroid carcinoma surgery in children and adolescents - 15 years experience surgery of pediatric thyroid carcinoma.
2013
2013
SAS1B protein [ovastacin] shows temporal and spatial restriction to oocytes in several eutherian orders and initiates translation at the primary to secondary follicle transition
Background: Sperm Acrosomal SLLP1 Binding (SAS1B) protein (ovastacin) is an oolemmal binding partner for the intra‐acrosomal… 
Highly Cited
2012
Highly Cited
2012
Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy
After fertilization, the metalloendoprotease ovastacin is released by cortical granule exocytosis and cleaves the zona pellucida… 
2012
2012
Oocyte specific oolemmal SAS1B involved in sperm binding through intra-acrosomal SLLP1 during fertilization.
Review
2010
Review
2010
An Evaluation of the Roche Cobas c 111
Background: The cobas c 111, a new low volume bench-top analyzer from Roche Diagnostics (Indianapolis, IN), was evaluated to… 
Highly Cited
2007
Highly Cited
2007
Microarray Analyses of Newborn Mouse Ovaries Lacking Nobox1
Abstract Nobox is a homeobox gene expressed in oocytes and critical in oogenesis. Nobox deficiency leads to rapid loss of… 
2006
2006
Purification, characterization and comparison of reptile lysozymes.
Highly Cited
2004
Highly Cited
2004
Identification and Characterization of Human and Mouse Ovastacin
We have cloned and characterized human and mouse ovary cDNAs encoding a new protein of the astacin family of metalloproteinases… 
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