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AS 1842856

Known as: AS-1842856, AS1842856 
National Institutes of Health

Papers overview

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2020
2020
Imipridone enhances vascular relaxation via FOXO1 pathway
Cardiovascular complications are a side effect of cancer therapy, potentially through reduced blood vessel function. ONC201… 
2018
2018
FAM3B (PANDER) functions as a co‐activator of FOXO1 to promote gluconeogenesis in hepatocytes
FAM3B, also known as PANcreatic DERived factor (PANDER), promotes gluconeogenesis and lipogenesis in hepatocytes. However, the… 
2018
2018
The Chromosome 21 Kinase DYRK1A and Its Substrate FOXO1 Constitute a Novel Therapeutic Pathway in B-ALL
Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase 1A (DYRK1A) is a serine/threonine kinase that regulates diverse… 
2018
2018
Abstract B17: FOXO1 is transcriptional regulator of malignant B-cell surface antigen CD20, the target for therapeutic monoclonal antibodies
Rituximab, a therapeutic anti-CD20 monoclonal antibody, is effective against B-cell malignancies, when combined with chemotherapy… 
2017
2017
The AMPK/mTOR pathway is involved in D‐dopachrome tautomerase gene transcription in adipocytes differentiated from SGBS cells, a human preadipocyte cell line
2017
2017
GSE86067: Antitumor effect of FOXO1 inhibitor AS1842856 on B-cell precursor acute lymphoblastic leukemia (BCP-ALL).
2016
2016
FoxO1 in the regulation of adipocyte autophagy and biology
ACADEMIC) Obesity is a rapidly growing epidemic in the USA and worldwide. While the molecular and cellular mechanism of obesity… 
2015
2015
Foxos Suppress Lipid Peroxidation to Promote AML Progression and Chemotherapy Resistance
Over 30% of acute myeloid leukemia (AML) patients do not respond to first-line chemotherapy, and a significant portion of… 
2015
2015
Novel application of FoxO1 selective inhibitor AS1842856
The invention discloses novel application of a FoxO1 selective inhibitor AS1842856. The novel application of a compound shown in… 
2015
2015
Nutrient availability and thyroid hormone activation 1 COUPLING BETWEEN NUTRIENT AVAILABILITY AND THYROID HORMONE ACTIVATION 1
The activity of the thyroid gland is stimulated by food availability via leptin-induced TRH/TSH expression. Here we show that… 
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