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ARX gene

Known as: ARX, Aristaless Related Homeobox Gene, aristaless related homeobox 
This gene plays a role in transcriptional regulation and the development of the brain.
National Institutes of Health

Related topics

Related topics

9 relations
ARX wt AlleleCell Differentiation processHomeobox Protein ARXHomo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Changes in Calcium Homeostasis and Gene Expression Implicated in Epilepsy in Hippocampi of Mice Overexpressing ORAI1
Previously, we showed that the overexpression of ORAI1 calcium channel in neurons of murine brain led to spontaneous occurrence… 
2018
2018
SIRT1 activation attenuates α cell hyperplasia, hyperglucagonaemia and hyperglycaemia in STZ-diabetic mice
The NAD+-dependent lysine deacetylase, Sirtuin 1 (SIRT1), plays a central role in metabolic regulation. With type 1 diabetes a… 
2017
2017
Aristaless Related Homeobox (ARX) Interacts with β-Catenin, BCL9, and P300 to Regulate Canonical Wnt Signaling
Mutations in the Aristaless Related Homeobox (ARX) gene are associated with a spectrum of structural (lissencephaly) and… 
2015
2015
The Role of ARX in Human Pancreatic Endocrine Specification
The in vitro differentiation of human embryonic stem cells (hESCs) offers a model system to explore human development. Humans… 
2015
2015
Expanding Pedestrian Injury Risk to the Body Region Level: How to Model Passive Safety Systems in Pedestrian Injury Risk Functions
Objective: Assessment of the effectiveness of advanced driver assistance systems (ADAS) plays a crucial role in accident research… 
2013
2013
Retinoblastoma tumor suppressor protein in pancreatic progenitors controls α- and β-cell fate
Pancreatic endocrine cells expand rapidly during embryogenesis by neogenesis and proliferation, but during adulthood, islet cells… 
2010
2010
Mutations in the nuclear localization sequence of the Aristaless related homeobox; sequestration of mutant ARX with IPO13 disrupts normal subcellular distribution of the transcription factor and…
BackgroundAristaless related homeobox (ARX) is a paired-type homeobox gene. ARX function is frequently affected by naturally… 
2009
2009
A novel de novo 27 bp duplication of the ARX gene, resulting from postzygotic mosaicism and leading to three severely affected males in two generations
The Aristaless Related Homeobox (ARX) gene is a Q50 paired homeobox gene. These genes are important regulators of essential… 
Highly Cited
2002
Highly Cited
2002
X-linked myoclonic epilepsy with spasticity and intellectual disability: Mutation in the homeobox gene ARX
ObjectiveTo describe a new syndrome of X-linked myoclonic epilepsy with generalized spasticity and intellectual disability… 
1997
1997
High-resolution genetic map of the Lv resistance locus in tomato
Abstract Bulked segregant analysis and high-resolution mapping were used to pinpoint the position of the Lv gene for resistance… 
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