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ARN-810

Known as: SERD ARN-810, Selective Estrogen Receptor Degrader ARN-810 
An orally available, nonsteroidal selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, SERD… Expand
National Institutes of Health

Papers overview

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2019
2019
Potent estrogen receptor ligands typically contain a phenolic hydrogen-bond donor. The indazole of the selective estrogen… Expand
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Highly Cited
2015
Highly Cited
2015
Approximately 80% of breast cancers are estrogen receptor alpha (ER-α) positive, and although women typically initially respond… Expand
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2015
2015
Background: Modulation of estrogen activity and/or synthesis is the mainstay therapeutic strategy in the treatment of estrogen… Expand
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2015
2015
Background: Evidence that ER can signal in both ligand-dependent and independent manner in endocrine resistant breast cancer (BC… Expand
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2015
2015
The majority of breast cancers express and rely on ERα for tumor growth, thus endocrine therapy is the mainstay of ER-positive… Expand
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2015
2015
Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA The majority of breast cancers express estrogen… Expand
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2014
2014
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA 80% of all breast cancers express the estrogen receptor… Expand
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2013
2013
Background: Modulation of estrogen synthesis or its receptor activity represents the treatment of choice for postmenopausal women… Expand
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2013
2013
Penelitian ini menggunakan metode eksperimen.Populasi dalam penelitian ini adalah seluruh siswa kelas X SMK Teknik Rekayasa Sinar… Expand
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