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ARN-810

Known as: SERD ARN-810, Selective Estrogen Receptor Degrader ARN-810 
An orally available, nonsteroidal selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon oral administration, SERD… 
National Institutes of Health

Papers overview

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2019
2019
Selective estrogen receptor degraders with novel structural motifs induce regression in a tamoxifen-resistant breast cancer xenograft.
2015
2015
Abstract P1-13-01: Phase I study of ARN-810, a novel and potent oral selective estrogen receptor degrader, in postmenopausal women with metastatic estrogen receptor positive (ER+), HER2- breast…
Background: Evidence that ER can signal in both ligand-dependent and independent manner in endocrine resistant breast cancer (BC… 
2015
2015
Validation of target engagement using 18F-fluoroestradiol PET in patients undergoing therapy with selective estrogen receptor degrader, ARN-810 (GDC-0810)
2015
2015
Abstract 5053: Discovery of GDC-0810 a novel, non-steroidal selective estrogen receptor degrader with robust activity in pre-clinical models of endocrine-resistant breast cancer
Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA The majority of breast cancers express estrogen… 
2015
2015
Abstract 1864: Selective estrogen receptor degrader (SERD) activity in ESR1 mutant models
The majority of breast cancers express and rely on ERα for tumor growth, thus endocrine therapy is the mainstay of ER-positive… 
2013
2013
Abstract OT3-2-07: Phase I study of ARN-810, a novel selective estrogen receptor degrader, in post-menopausal women with locally advanced or metastatic estrogen receptor positive breast cancer
Background: Modulation of estrogen synthesis or its receptor activity represents the treatment of choice for postmenopausal women… 
2013
2013
PERBEDAAN HASIL BELAJAR SISWA MENGGUNAKAN MODEL PEMBELAJARAN KOOPERATIF TIPE THINK TALK WRITE (TTW) DENGAN MODEL PEMBELAJARAN KONVENSIONAL (CERAMAH) PADA STANDART KOMPETENSI MENGGUNAKAN ALAT-ALAT…
Penelitian ini menggunakan metode eksperimen.Populasi dalam penelitian ini adalah seluruh siswa kelas X SMK Teknik Rekayasa Sinar… 
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