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ARL4C gene

Known as: ARL4C, ADP ribosylation factor like GTPase 4C, ADP-RIBOSYLATION FACTOR-LIKE 7 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
ARL4C is associated with initiation and progression of lung adenocarcinoma and represents a therapeutic target
Lung adenocarcinoma is the most common histological type of lung cancer and is classified into adenocarcinoma in situ (AIS… 
2019
2019
Chemically Modified Antisense Oligonucleotide Against ARL4C Inhibits Primary and Metastatic Liver Tumor Growth
ADP-ribosylation factor-like 4c (ARL4C) is identified as a small GTP-binding protein, which is expressed by Wnt and EGF signaling… 
2018
2018
Identification of ARL4C as a Peritoneal Dissemination-Associated Gene and Its Clinical Significance in Gastric Cancer
BackgroundIn gastric cancer (GC), peritoneal dissemination (PD) occurs frequently and is incurable. In this study, we aimed to… 
Review
2017
Review
2017
Arl4c is a key regulator of tubulogenesis and tumourigenesis as a target gene of Wnt-β-catenin and growth factor-Ras signalling.
Epithelial tubular morphogenesis (tubulogenesis) is a fundamental morphogenetic process of many epithelial organs. In this… 
2016
2016
Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3'-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma
ADP-ribosylation factor (ARF)-like 4c (ARL4C) expression, induced by a combination of Wnt/β-catenin and EGF/Ras signaling, has… 
2015
2015
ADP-ribosylation factor-like 4C (ARL4C), a novel ovarian cancer metastasis suppressor, identified by integrated genomics.
Understanding the molecular mechanisms involving the initiation, progression, and metastasis of ovarian cancer is important for… 
Highly Cited
2014
Highly Cited
2014
A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures
Growth factor‐dependent epithelial morphological changes and proliferation are essential for the formation of tubular structures… 
Highly Cited
2014
Highly Cited
2014
Arl4c expression in colorectal and lung cancers promotes tumorigenesis and may represent a novel therapeutic target
We recently demonstrated that expression of ADP-ribosylation factor (ARF)-like 4c (Arl4c) induced by a combination of Wnt… 
Highly Cited
2012
Highly Cited
2012
Novel Pathways in the Pathobiology of Human Abdominal Aortic Aneurysms
Objectives: Abdominal aortic aneurysm (AAA), a dilatation of the infrarenal aorta, typically affects males >65 years. The… 
Highly Cited
2004
Highly Cited
2004
ADP‐ribosylation factor (ARF)‐like 7 (ARL7) is induced by cholesterol loading and participates in apolipoprotein AI‐dependent cholesterol export
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