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ARL2 gene

Known as: ADP-RIBOSYLATION FACTOR-LIKE 2, ARL2, ADP ribosylation factor like GTPase 2 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
A PDE6δ-KRas Inhibitor Chemotype with up to Seven H-Bonds and Picomolar Affinity that Prevents Efficient Inhibitor Release by Arl2.
Small-molecule inhibition of the interaction between the KRas oncoprotein and the chaperone PDE6δ impairs KRas spatial… 
Review
2016
Review
2016
Sorting of lipidated cargo by the Arl2/Arl3 system
ABSTRACT Arl2 and Arl3 are Arf-like small GTP-binding proteins of the Arf subfamily of the Ras superfamily. Despite their… 
2016
2016
Coumarin-thiazole and -oxadiazole derivatives: Synthesis, bioactivity and docking studies for aldose/aldehyde reductase inhibitors.
Highly Cited
2015
Highly Cited
2015
Tubulin cofactors and Arl2 are cage-like chaperones that regulate the soluble αβ-tubulin pool for microtubule dynamics
Microtubule dynamics and polarity stem from the polymerization of αβ-tubulin heterodimers. Five conserved tubulin cofactors… 
Review
2012
Review
2012
The prenyl-binding protein PrBP/δ: A chaperone participating in intracellular trafficking
Highly Cited
2011
Highly Cited
2011
Molecular and Cellular Pathobiology Intracellular CD 24 Inhibits Cell Invasion by Posttranscriptional Regulation of BART through Interaction with G 3 BP
We report a novel function for the CD24 molecule in pancreatic cancer cells. Intracellular CD24 is associated with stress… 
2010
2010
Effect of TBCD and its regulatory interactor Arl2 on tubulin and microtubule integrity
Assembly of the α/β tubulin heterodimer requires the participation of a series of chaperone proteins (TBCA‐E) that function… 
Highly Cited
2003
Highly Cited
2003
Cytosolic Arl2 Is Complexed with Cofactor D and Protein Phosphatase 2A*
Arl2 is a member of the ADP-ribosylation factor family of 20-kDa GTPases that is highly conserved in eukaryotes. Recent results… 
Highly Cited
2001
Highly Cited
2001
ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) Have Both Specific and Shared Effectors
Despite the 40–60% identity between ADP-ribosylation factors (ARFs) and ARF-like (ARL) proteins, distinct functional roles have… 
Highly Cited
1993
Highly Cited
1993
Selective amplification of additional members of the ADP-ribosylation factor (ARF) family: cloning of additional human and Drosophila ARF-like genes.
The ADP-ribosylation factor (ARF) family is one of four subfamilies of the RAS superfamily of low molecular weight GTP-binding… 
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