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ARHGEF26 gene

Known as: DKFZP434D146, Rho guanine nucleotide exchange factor 26, ARHGEF26 
National Institutes of Health

Papers overview

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2019
2019
SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility
Awadia et al. show that SGEF, a RhoG-specific GEF, forms a ternary complex with two members of the Scribble polarity complex… 
Highly Cited
2017
Highly Cited
2017
Identification of 15 novel risk loci for coronary artery disease and genetic risk of recurrent events, atrial fibrillation and heart failure
Coronary artery disease (CAD) is the major cause of morbidity and mortality in the world. Identification of novel genetic… 
2017
2017
A RhoG-mediated signaling pathway that modulates invadopodia dynamics in breast cancer cells
ABSTRACT One of the hallmarks of cancer is the ability of tumor cells to invade surrounding tissues and metastasize. During… 
2016
2016
SGEF Is Regulated via TWEAK/Fn14/NF-κB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide
Glioblastoma (GB) is the highest grade and most common form of primary adult brain tumors. Despite surgical removal followed by… 
2016
2016
Dicer generates a regulatory microRNA network in smooth muscle cells that limits neointima formation during vascular repair
MicroRNAs (miRNAs) coordinate vascular repair by regulating injury-induced gene expression in vascular smooth muscle cells (SMCs… 
2013
2013
The Guanine-Nucleotide Exchange Factor SGEF Plays a Crucial Role in the Formation of Atherosclerosis
The passage of leukocytes across the endothelium and into arterial walls is a critical step in the development of atherosclerosis… 
2013
2013
The Src Homology 3 Domain-containing Guanine Nucleotide Exchange Factor Is Overexpressed in High-grade Gliomas and Promotes Tumor Necrosis Factor-like Weak Inducer of Apoptosis-Fibroblast Growth…
Background: Glioblastoma is characterized by heightened cell invasion and therapeutic resistance. Results: The Src homology 3… 
2012
2012
The Invasive Capacity of HPV Transformed Cells Requires the hDlg-Dependent Enhancement of SGEF/RhoG Activity
A major target of the HPV E6 oncoprotein is the human Discs Large (hDlg) tumour suppressor, although how this interaction… 
Highly Cited
2004
Highly Cited
2004
SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis.
SGEF (SH3-containing Guanine Nucleotide Exchange Factor) is a RhoGEF of unknown function. We found the SGEF protein to be… 
2003
2003
Isolation of the novel human guanine nucleotide exchange factor Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF) and of C-terminal SGEF, an N-terminally truncated form of…
In searching for androgen-responsive genes in human prostate cancer cells, we have isolated two cDNAs that encode alternate forms… 
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