ARHGAP31 gene

Known as: Rho GTPase activating protein 31, KIAA1204, CDGAP 
 
National Institutes of Health

Papers overview

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2016
2016
Cdc42 and k-Ras Control Endothelial Tubulogenesis through Apical Membrane and Cytoskeletal Polarization: Novel Stimulatory Roles for GTPase Effectors, the Small GTPases, Rac2 and Rap1b, and…
A critical and understudied property of endothelial cells is their ability to form lumens and tube networks. Although… (More)
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2014
2014
Isolated terminal limb reduction defects: extending the clinical spectrum of Adams-Oliver syndrome and ARHGAP31 mutations.
Adams-Oliver syndrome (AOS; OMIM 100300) typically comprises a combination of congenital scalp defects and terminal transverse… (More)
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2014
2014
The Focal Adhesion-Localized CdGAP Regulates Matrix Rigidity Sensing and Durotaxis
Motile cells are capable of sensing the stiffness of the surrounding extracellular matrix through integrin-mediated focal… (More)
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2012
2012
CdGAP regulates cell migration and adhesion dynamics in two-and three-dimensional matrix environments.
CdGAP is a Rac1/Cdc42 specific GTPase activating protein (GAP) that localizes to cell-matrix adhesions through an interaction… (More)
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2011
2011
ARHGAP30 is a Wrch-1-interacting protein involved in actin dynamics and cell adhesion.
The atypical Rho GTPase Wrch-1 has been proposed roles in cell migration, focal adhesion dissolution, stress fibre break down and… (More)
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2010
2010
Hepatocyte Growth Factor stimulated cell scattering requires ERK and Cdc42-dependent tight junction disassembly.
The mechanism by which Hepatocyte Growth Factor (HGF) induces tight junction disassembly prior to cell scattering is largely… (More)
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2007
2007
Focal adhesion kinase controls morphogenesis of the Drosophila optic stalk.
Photoreceptor cell axons (R axons) innervate optic ganglia in the Drosophila brain through the tubular optic stalk. This… (More)
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2005
2005
Extracellular signal-regulated kinase 1 interacts with and phosphorylates CdGAP at an important regulatory site.
Rho GTPases regulate multiple cellular processes affecting both cell proliferation and cytoskeletal dynamics. Their cycling… (More)
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2003
2003
GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2.
Gab1 and Gab2 are scaffolding proteins acting downstream of cell surface receptors and interact with a variety of cytoplasmic… (More)
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Highly Cited
2002
Highly Cited
2002
Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells.
Rho family G proteins, including Rac and Cdc42, regulate a variety of cellular functions such as morphology, motility, and gene… (More)
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