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ARHGAP31 gene

Known as: Rho GTPase activating protein 31, KIAA1204, CDGAP 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
The Focal Adhesion-Localized CdGAP Regulates Matrix Rigidity Sensing and Durotaxis
Motile cells are capable of sensing the stiffness of the surrounding extracellular matrix through integrin-mediated focal… 
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2009
2009
Validation Study of Genetic Associations with Coronary Artery Disease on Chromosome 3q13‐21 and Potential Effect Modification by Smoking
The CATHGEN study reported associations of chromosome 3q13‐21 genes (KALRN, MYLK, CDGAP, and GATA2) with early‐onset coronary… 
Review
2007
Review
2007
Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease.
A susceptibility locus for coronary artery disease (CAD) has been mapped to chromosome 3q13-21 in a linkage study of early-onset… 
2007
2007
Focal adhesion kinase controls morphogenesis of the Drosophila optic stalk
Photoreceptor cell axons (R axons) innervate optic ganglia in the Drosophila brain through the tubular optic stalk. This… 
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Highly Cited
2006
Highly Cited
2006
CdGAP Associates with Actopaxin to Regulate Integrin-Dependent Changes in Cell Morphology and Motility
BACKGROUND Integrin signaling, stimulated by cell adhesion to the extracellular matrix, plays a critical role in coordinating… 
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2005
2005
Extracellular Signal-Regulated Kinase 1 Interacts with and Phosphorylates CdGAP at an Important Regulatory Site
ABSTRACT Rho GTPases regulate multiple cellular processes affecting both cell proliferation and cytoskeletal dynamics. Their… 
Highly Cited
2003
Highly Cited
2003
GC-GAP, a Rho Family GTPase-activating Protein That Interacts with Signaling Adapters Gab1 and Gab2*
Gab1 and Gab2 are scaffolding proteins acting downstream of cell surface receptors and interact with a variety of cytoplasmic… 
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Highly Cited
2002
Highly Cited
2002
Activation of Rac and Cdc42 Video Imaged by Fluorescent Resonance Energy Transfer-Based Single-Molecule Probes in the Membrane of Living Cells
ABSTRACT Rho family G proteins, including Rac and Cdc42, regulate a variety of cellular functions such as morphology, motility… 
Highly Cited
2002
Highly Cited
2002
The Activity of the GTPase-activating Protein CdGAP Is Regulated by the Endocytic Protein Intersectin*
The Rho GTPases RhoA, Rac1, and Cdc42 play a major role in regulating the reorganization of the actin cytoskeleton. We recently… 
Highly Cited
1998
Highly Cited
1998
CdGAP, a Novel Proline-rich GTPase-activating Protein for Cdc42 and Rac*
Cdc42 mediates several signaling pathways leading to actin reorganization, transcriptional activation, and cell cycle control… 
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