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APOB protein, human
Known as:
ApoB100 danger-associated signal 1 protein, human
, APOB
, apolipoprotein B-100 protein, human
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Apolipoprotein B-100 (4563 aa, ~516 kDa) is encoded by the human APOB gene. This protein plays a role in both transport and cellular uptake of LDL…
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National Institutes of Health
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Related topics
Related topics
14 relations
APOB gene
Apolipoprotein B Assay
Apolipoprotein B100 Measurement
Apolipoproteins B
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Broader (1)
Apolipoprotein B-100
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells.
J. Kopecka
,
I. Campia
,
+4 authors
C. Riganti
Journal of controlled release : official journal…
2011
Corpus ID: 37262625
2011
2011
Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins.
A. Hayashi
,
Jennifer P. Webb
,
+6 authors
K. Adeli
American journal of physiology. Gastrointestinal…
2011
Corpus ID: 17468360
Intestinal lipid dysregulation is a common feature of insulin-resistant states. The present study investigated alterations in…
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Highly Cited
2007
Highly Cited
2007
Dietary Fat–Induced Alterations in Atherosclerosis Are Abolished by ACAT2-Deficiency in ApoB100 Only, LDLr−/− Mice
T. Bell
,
K. Kelley
,
Martha D. Wilson
,
J. Sawyer
,
L. Rudel
Arteriosclerosis, thrombosis, and vascular…
2007
Corpus ID: 12748628
Objectives—The enzyme acyl-coenzymeA (CoA):cholesterol O-acyltransferase 2 (ACAT2) in the liver synthesizes cholesteryl esters…
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Highly Cited
2005
Highly Cited
2005
Hepatitis C Virus Nonstructural Proteins Inhibit Apolipoprotein B100 Secretion*
A. M. Domitrovich
,
D. Felmlee
,
A. Siddiqui
Journal of Biological Chemistry
2005
Corpus ID: 21179664
Host genes involved in lipid metabolism are differentially regulated during the early stages of hepatitis C virus (HCV) infection…
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2004
2004
A broad-based metabolic approach to study VLDL apoB100 metabolism in patients with ESRD and patients treated with peritoneal dialysis.
B. Prinsen
,
T. Rabelink
,
+7 authors
M. G. M. de Sain-van der Velden
Kidney international
2004
Corpus ID: 21620938
BACKGROUND Dyslipidemia is often observed in patients with end-stage renal disease (ESRD) and is associated with cardiovascular…
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Highly Cited
2000
Highly Cited
2000
Short- and long-term effects of atorvastatin, lovastatin and simvastatin on the cellular metabolism of cholesteryl esters and VLDL secretion in rat hepatocytes.
E. Isusi
,
P. Aspichueta
,
+5 authors
B. Ochoa
Atherosclerosis
2000
Corpus ID: 22282620
Highly Cited
1997
Highly Cited
1997
The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor.
K. Argraves
,
K. Kozarsky
,
J. Fallon
,
P. Harpel
,
D. Strickland
The Journal of clinical investigation
1997
Corpus ID: 8000458
Lp(a) is a major inherited risk factor associated with premature heart disease and stroke. The mechanism of Lp(a) atherogenicity…
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1997
1997
Transgenic Mice Expressing Human ApoB95 and ApoB97
S. Mccormick
,
J. K. Ng
,
+5 authors
S. Young
The Journal of Biological Chemistry
1997
Corpus ID: 30939631
The structural features of apolipoprotein (apo) B that are important for its covalent linkage to apo(a) to form lipoprotein(a…
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Highly Cited
1995
Highly Cited
1995
Degradation of Apolipoprotein B in Cultured Rat Hepatocytes Occurs in a Post-endoplasmic Reticulum Compartment (*)
Chuen-Neu Wang
,
T. Hobman
,
D. Brindley
The Journal of Biological Chemistry
1995
Corpus ID: 45833818
The site of apolipoprotein B (apoB) degradation was investigated in cultured rat hepatocytes. Brefeldin A plus nocodazole…
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Highly Cited
1994
Highly Cited
1994
Carboxyl-terminal truncation impairs lipid recruitment by apolipoprotein B100 but does not affect secretion of the truncated apolipoprotein B-containing lipoproteins.
R. McLeod
,
Y. Zhao
,
S. L. Selby
,
J. Westerlund
,
Z. Yao
The Journal of biological chemistry
1994
Corpus ID: 202818
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