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APOB protein, human

Known as: ApoB100 danger-associated signal 1 protein, human, APOB, apolipoprotein B-100 protein, human 
Apolipoprotein B-100 (4563 aa, ~516 kDa) is encoded by the human APOB gene. This protein plays a role in both transport and cellular uptake of LDL… Expand
National Institutes of Health

Related topics

Related topics

14 relations
APOB geneApolipoprotein B AssayApolipoprotein B100 MeasurementApolipoproteins B
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Broader (1)

Apolipoprotein B-100

Papers overview

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2011
2011
A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells.
Doxorubicin is one of the most employed anticancer drugs, but its efficacy is limited by the onset of adverse effects such as… Expand
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2004
2004
A broad-based metabolic approach to study VLDL apoB100 metabolism in patients with ESRD and patients treated with peritoneal dialysis.
BACKGROUND Dyslipidemia is often observed in patients with end-stage renal disease (ESRD) and is associated with cardiovascular… Expand
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2004
2004
Overexpression of the endoplasmic reticulum 60 protein ER-60 downregulates apoB100 secretion by inducing its intracellular degradation via a nonproteasomal pathway: evidence for an ER-60-mediated and…
Co- and posttranslational regulation of apolipoprotein B (apoB) has been postulated to involve degradation by both proteasomal… Expand
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2003
2003
Identification of Lipoproteins of Intestinal Origin in Human Atherosclerotic Plaque
Abstract Apolipoproteins (apo) B48 and B100 are exclusive markers of lipoproteins derived from the intestine and liver… Expand
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2000
2000
Short- and long-term effects of atorvastatin, lovastatin and simvastatin on the cellular metabolism of cholesteryl esters and VLDL secretion in rat hepatocytes.
The short- and long-term in vitro effects of the hydroxymethylglutaryl-CoA reductase inhibitor atorvastatin, compared with… Expand
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2000
2000
A deficiency of microsomal triglyceride transfer protein reduces apolipoprotein B secretion.
Microsomal triglyceride transfer protein (MTP) transfers lipids to apolipoprotein B (apoB) within the endoplasmic reticulum, a… Expand
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Highly Cited
1997
Highly Cited
1997
The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor.
Lp(a) is a major inherited risk factor associated with premature heart disease and stroke. The mechanism of Lp(a) atherogenicity… Expand
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1996
1996
Role of the Golgi apparatus in the phosphorylation of apolipoprotein B.
  • Larry L Swift
  • The Journal of biological chemistry
  • 1996
    • Corpus ID: 37727154
Rat hepatic Golgi apparatus-rich fractions were utilized in an in vitro phosphorylation system containing [gamma-32P]ATP to… Expand
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1995
1995
Degradation of apolipoprotein B in cultured rat hepatocytes occurs in a post-endoplasmic reticulum compartment.
The site of apolipoprotein B (apoB) degradation was investigated in cultured rat hepatocytes. Brefeldin A plus nocodazole… Expand
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Review
1994
Review
1994
Transgenic mice expressing human apoB100 and apoB48.
Transgenic mice that express human apolipoprotein (apo)B have been developed by microinjecting fertilized mouse oocytes with an… Expand
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