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APOB protein, human

Known as: ApoB100 danger-associated signal 1 protein, human, APOB, apolipoprotein B-100 protein, human 
Apolipoprotein B-100 (4563 aa, ~516 kDa) is encoded by the human APOB gene. This protein plays a role in both transport and cellular uptake of LDL… Expand
National Institutes of Health

Related topics

Related topics

14 relations
APOB geneApolipoprotein B AssayApolipoprotein B100 MeasurementApolipoproteins B
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Broader (1)

Apolipoprotein B-100

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells.
Doxorubicin is one of the most employed anticancer drugs, but its efficacy is limited by the onset of adverse effects such as… Expand
2009
2009
Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling
Glucosamine impairs hepatic apolipoprotein B100 (apoB100) production by inducing endoplasmic reticulum (ER) stress and enhancing… Expand
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Highly Cited
2007
Highly Cited
2007
Dietary Fat–Induced Alterations in Atherosclerosis Are Abolished by ACAT2-Deficiency in ApoB100 Only, LDLr−/− Mice
Objectives—The enzyme acyl-coenzymeA (CoA):cholesterol O-acyltransferase 2 (ACAT2) in the liver synthesizes cholesteryl esters… Expand
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2006
2006
Translocation Efficiency of Apolipoprotein B Is Determined by the Presence of β-Sheet Domains, Not Pause Transfer Sequences*
Cotranslational translocation of apoB100 across the endoplasmic reticulum (ER) membrane is inefficient, resulting in exposure of… Expand
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Highly Cited
2005
Highly Cited
2005
Hepatitis C Virus Nonstructural Proteins Inhibit Apolipoprotein B100 Secretion*
Host genes involved in lipid metabolism are differentially regulated during the early stages of hepatitis C virus (HCV) infection… Expand
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2004
2004
A broad-based metabolic approach to study VLDL apoB100 metabolism in patients with ESRD and patients treated with peritoneal dialysis.
BACKGROUND Dyslipidemia is often observed in patients with end-stage renal disease (ESRD) and is associated with cardiovascular… Expand
Highly Cited
2000
Highly Cited
2000
Short- and long-term effects of atorvastatin, lovastatin and simvastatin on the cellular metabolism of cholesteryl esters and VLDL secretion in rat hepatocytes.
The short- and long-term in vitro effects of the hydroxymethylglutaryl-CoA reductase inhibitor atorvastatin, compared with… Expand
Highly Cited
1997
Highly Cited
1997
The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor.
Lp(a) is a major inherited risk factor associated with premature heart disease and stroke. The mechanism of Lp(a) atherogenicity… Expand
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1996
1996
Role of the Golgi apparatus in the phosphorylation of apolipoprotein B.
  • L. Swift
  • The Journal of biological chemistry
  • 1996
    • Corpus ID: 37727154
Rat hepatic Golgi apparatus-rich fractions were utilized in an in vitro phosphorylation system containing [gamma-32P]ATP to… Expand
Highly Cited
1995
Highly Cited
1995
Degradation of Apolipoprotein B in Cultured Rat Hepatocytes Occurs in a Post-endoplasmic Reticulum Compartment (*)
The site of apolipoprotein B (apoB) degradation was investigated in cultured rat hepatocytes. Brefeldin A plus nocodazole… Expand
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