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APOB protein, human

Known as: ApoB100 danger-associated signal 1 protein, human, APOB, apolipoprotein B-100 protein, human 
Apolipoprotein B-100 (4563 aa, ~516 kDa) is encoded by the human APOB gene. This protein plays a role in both transport and cellular uptake of LDL… 
National Institutes of Health

Related topics

Related topics

14 relations
APOB geneApolipoprotein B AssayApolipoprotein B100 MeasurementApolipoproteins B

Broader (1)

Apolipoprotein B-100

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins.
Intestinal lipid dysregulation is a common feature of insulin-resistant states. The present study investigated alterations in… 
Highly Cited
2011
Highly Cited
2011
A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells.
Highly Cited
2009
Highly Cited
2009
Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling
Glucosamine impairs hepatic apolipoprotein B100 (apoB100) production by inducing endoplasmic reticulum (ER) stress and enhancing… 
Review
2009
Review
2009
Therapeutic regulation of apoB100 metabolism in insulin resistance in vivo.
2006
2006
Translocation Efficiency of Apolipoprotein B Is Determined by the Presence of β-Sheet Domains, Not Pause Transfer Sequences*
Cotranslational translocation of apoB100 across the endoplasmic reticulum (ER) membrane is inefficient, resulting in exposure of… 
Highly Cited
2000
Highly Cited
2000
Short- and long-term effects of atorvastatin, lovastatin and simvastatin on the cellular metabolism of cholesteryl esters and VLDL secretion in rat hepatocytes.
Highly Cited
1997
Highly Cited
1997
The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor.
Lp(a) is a major inherited risk factor associated with premature heart disease and stroke. The mechanism of Lp(a) atherogenicity… 
1996
1996
Role of the Golgi apparatus in the phosphorylation of apolipoprotein B.
Rat hepatic Golgi apparatus-rich fractions were utilized in an in vitro phosphorylation system containing [gamma-32P]ATP to… 
Highly Cited
1995
Highly Cited
1995
Degradation of Apolipoprotein B in Cultured Rat Hepatocytes Occurs in a Post-endoplasmic Reticulum Compartment (*)
The site of apolipoprotein B (apoB) degradation was investigated in cultured rat hepatocytes. Brefeldin A plus nocodazole… 
Highly Cited
1994
Highly Cited
1994
Carboxyl-terminal truncation impairs lipid recruitment by apolipoprotein B100 but does not affect secretion of the truncated apolipoprotein B-containing lipoproteins.
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