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APOB protein, human

Known as: ApoB100 danger-associated signal 1 protein, human, APOB, apolipoprotein B-100 protein, human 
Apolipoprotein B-100 (4563 aa, ~516 kDa) is encoded by the human APOB gene. This protein plays a role in both transport and cellular uptake of LDL… 
National Institutes of Health

Related topics

Related topics

14 relations
APOB geneApolipoprotein B AssayApolipoprotein B100 MeasurementApolipoproteins B

Broader (1)

Apolipoprotein B-100

Papers overview

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Highly Cited
2011
Highly Cited
2011
A LDL-masked liposomal-doxorubicin reverses drug resistance in human cancer cells.
2011
2011
Intestinal SR-BI is upregulated in insulin-resistant states and is associated with overproduction of intestinal apoB48-containing lipoproteins.
Intestinal lipid dysregulation is a common feature of insulin-resistant states. The present study investigated alterations in… 
Highly Cited
2007
Highly Cited
2007
Dietary Fat–Induced Alterations in Atherosclerosis Are Abolished by ACAT2-Deficiency in ApoB100 Only, LDLr−/− Mice
Objectives—The enzyme acyl-coenzymeA (CoA):cholesterol O-acyltransferase 2 (ACAT2) in the liver synthesizes cholesteryl esters… 
Highly Cited
2005
Highly Cited
2005
Hepatitis C Virus Nonstructural Proteins Inhibit Apolipoprotein B100 Secretion*
Host genes involved in lipid metabolism are differentially regulated during the early stages of hepatitis C virus (HCV) infection… 
2004
2004
A broad-based metabolic approach to study VLDL apoB100 metabolism in patients with ESRD and patients treated with peritoneal dialysis.
BACKGROUND Dyslipidemia is often observed in patients with end-stage renal disease (ESRD) and is associated with cardiovascular… 
Highly Cited
2000
Highly Cited
2000
Short- and long-term effects of atorvastatin, lovastatin and simvastatin on the cellular metabolism of cholesteryl esters and VLDL secretion in rat hepatocytes.
Highly Cited
1997
Highly Cited
1997
The atherogenic lipoprotein Lp(a) is internalized and degraded in a process mediated by the VLDL receptor.
Lp(a) is a major inherited risk factor associated with premature heart disease and stroke. The mechanism of Lp(a) atherogenicity… 
1997
1997
Transgenic Mice Expressing Human ApoB95 and ApoB97
The structural features of apolipoprotein (apo) B that are important for its covalent linkage to apo(a) to form lipoprotein(a… 
Highly Cited
1995
Highly Cited
1995
Degradation of Apolipoprotein B in Cultured Rat Hepatocytes Occurs in a Post-endoplasmic Reticulum Compartment (*)
The site of apolipoprotein B (apoB) degradation was investigated in cultured rat hepatocytes. Brefeldin A plus nocodazole… 
Highly Cited
1994
Highly Cited
1994
Carboxyl-terminal truncation impairs lipid recruitment by apolipoprotein B100 but does not affect secretion of the truncated apolipoprotein B-containing lipoproteins.
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