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APG101
Known as:
CD95 ECD/IgG-Fc Fusion Protein APG101
A human, soluble fusion protein consisting of the extracellular domain of the CD95 receptor fused to the Fc-domain of the human IgG antibody, with…
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National Institutes of Health
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Related topics
Related topics
4 relations
Broader (3)
CD95 Antigens
Immunoglobulin G
Recombinant Fusion Proteins
NCIt Antineoplastic Agent Terminology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Abstract 464: Methylation of a single CpG site in the CD95-ligand promoter is a biomarker predicting the response to therapy with APG101 in glioblastoma
C. Gieffers
,
C. Kunz
,
+5 authors
W. Wick
2016
Corpus ID: 78786154
Review
2015
Review
2015
Abstract A115: The CD95 ligand inhibitor APG 101 reduces tumor recurrence and metastasis in an adjuvant orthotopic mouse model of pancreatic cancer as well as primary tumor load in a palliative…
Freya A. Goumas
,
Khalid Rhashid
,
+5 authors
H. Kalthoff
2015
Corpus ID: 69129202
Since the first description of CD95/Fas this member of the death receptor superfamily has been regarded as paradigmatic for death…
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2014
2014
Cancer Therapy : Clinical A Phase II , Randomized , Study of Weekly APG 101 þ Reirradiation versus Reirradiation in Progressive Glioblastoma
W. Wick
,
H. Fricke
,
+14 authors
S. Combs
2014
Corpus ID: 29797666
Purpose: Preclinical data indicate anti-invasive activity of APG101, a CD95 ligand (CD95L)–binding fusion protein, in…
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