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APC 8015

Known as: APC-8015, APC8015, APC8015 Vaccine 
A cell-based vaccine composed of autologous antigen-presenting peripheral blood mononuclear cells (enriched for a dendritic cell fraction) that have… Expand
National Institutes of Health

Related topics

Related topics

3 relations
Dendritic CellsProvenge

Broader (1)

sipuleucel-T

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Prostate Cancer Immunotherapy with Sipuleucel-T: Current Standards and Future Directions
The management of advanced prostate cancer, specifically metastatic castrate-resistant prostate cancer (mCRPC), remains a… Expand
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Review
2011
Review
2011
Vaccine therapy with sipuleucel-T (Provenge) for prostate cancer.
As the most common malignancy among North American males, prostate cancer causes more than 30,000 deaths each year. After local… Expand
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Review
2007
Review
2007
Advances in Prostate Cancer Immunotherapies
Prostate cancer is a major cause of mortality in men in the Western world. Although treatment of early stage prostate cancer with… Expand
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2007
2007
Placebo-Controlled Phase III Trial of Immunologic Therapy with Sipuleucel-T (APC8015) in Patients with Metastatic, Asymptomatic Hormone Refractory Prostate Cancer: Small EJ, Schellhammer PF, Higano…
 
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Highly Cited
2006
Highly Cited
2006
Placebo-controlled phase III trial of immunologic therapy with sipuleucel-T (APC8015) in patients with metastatic, asymptomatic hormone refractory prostate cancer.
PURPOSE Sipuleucel-T (APC8015) is an investigational immunotherapy product designed to stimulate T-cell immunity against… Expand
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Highly Cited
2006
Highly Cited
2006
Combination immunotherapy with prostatic acid phosphatase pulsed antigen-presenting cells (provenge) plus bevacizumab in patients with serologic progression of prostate cancer after definitive local…
BACKGROUND APC8015 (sipuleucel-T) is a cellular prostate cancer vaccine containing autologous antigen-presenting cells (APC… Expand
Is this relevant?
2005
2005
Antigen-presenting cells 8015 (Provenge) in patients with androgen-dependent, biochemically relapsed prostate cancer.
BACKGROUND Antigen-presenting cells 8015 (APC8015; Provenge) is an immunotherapeutic product designed to initiate a T-cell… Expand
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Highly Cited
2004
Highly Cited
2004
Immunotherapy (APC8015, Provenge) targeting prostatic acid phosphatase can induce durable remission of metastatic androgen-independent prostate cancer: a Phase 2 trial.
BACKGROUND Prostate cancer is the most commonly diagnosed malignancy in American men, yet treatment of its metastatic androgen… Expand
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Review
2002
Review
2002
Technology evaluation: APC-8015, Dendreon.
  • Brian I. Rini
  • Current opinion in molecular therapeutics
  • 2002
    • Corpus ID: 43594022
Dendreon (formerly Activated Cell Therapy), in association with the Mayo Clinic, is developing the dendritic cell therapy APC… Expand
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Highly Cited
2000
Highly Cited
2000
Priming tissue-specific cellular immunity in a phase I trial of autologous dendritic cells for prostate cancer.
We attempted to induce therapeutic immunity against prostate-derived tissues in patients suffering from progressive hormone… Expand
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